Myosin light chain kinase ( MYLK) coding polymorphisms modulate human lung endothelial cell barrier responses via altered tyrosine phosphorylation, spatial localization, and lamellipodial protrusions. (Q54124538)

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English	Myosin light chain kinase ( MYLK) coding polymorphisms modulate human lung endothelial cell barrier responses via altered tyrosine phosphorylation, spatial localization, and lamellipodial protrusions.	scientific article

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18 March 2020

Myosin light chain kinase ( MYLK) coding polymorphisms modulate human lung endothelial cell barrier responses via altered tyrosine phosphorylation, spatial localization, and lamellipodial protrusions (English)

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18 March 2020

phosphorylation

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Gabriel T Kelly

3

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18 March 2020

Joseph B Mascarenhas

5

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18 March 2020

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Ting Wang

1

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18 March 2020

Mary E Brown

2

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18 March 2020

Sara M Camp

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18 March 2020

Xiaoguang Sun

6

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18 March 2020

Steven M Dudek

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18 March 2020

Joe G N Garcia

8

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18 March 2020

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26 February 2018

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18 March 2020

Pulmonary circulation

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18 March 2020

8

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18 March 2020

2

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18 March 2020

2045894018764171

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Europe PubMed Central

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18 March 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5846938/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Differential elastic responses to barrier-altering agonists in two types of human lung endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Structure-Function Analysis of the Non-Muscle Myosin Light Chain Kinase (nmMLCK) Isoform by NMR Spectroscopy and Molecular Modeling: Influence of MYLK Variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Nano-Biomechanical Study of Spatio-Temporal Cytoskeleton Rearrangements that Determine Subcellular Mechanical Properties and Endothelial Permeability

1 reference

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25 May 2018

Fine mapping of the myosin light chain kinase (MYLK) gene replicates the association with asthma in populations of Spanish descent

1 reference

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25 May 2018

A MYLK variant regulates asthmatic inflammation via alterations in mRNA secondary structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Proline-rich region of non-muscle myosin light chain kinase modulates kinase activity and endothelial cytoskeletal dynamics

1 reference

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25 May 2018

Asthma in Hispanics. An 8-year update

1 reference

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25 May 2018

Nonmuscle myosin light chain kinase regulates murine asthmatic inflammation

1 reference

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25 May 2018

Heterogeneous elastic response of human lung microvascular endothelial cells to barrier modulating stimuli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Abl tyrosine kinase phosphorylates nonmuscle Myosin light chain kinase to regulate endothelial barrier function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Quantitative distribution and colocalization of non-muscle myosin light chain kinase isoforms and cortactin in human lung endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Variation in the myosin light chain kinase gene is associated with development of acute lung injury after major trauma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Endothelial permeability is controlled by spatially defined cytoskeletal mechanics: atomic force microscopy force mapping of pulmonary endothelial monolayer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Novel polymorphisms in the myosin light chain kinase gene confer risk for acute lung injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Race and gender differences in acute respiratory distress syndrome deaths in the United States: an analysis of multiple-cause mortality data (1979- 1996).

1 reference

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25 May 2018

Hepatocyte growth factor enhances endothelial cell barrier function and cortical cytoskeletal rearrangement: potential role of glycogen synthase kinase-3beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Cytoskeletal regulation of pulmonary vascular permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Differential regulation of alternatively spliced endothelial cell myosin light chain kinase isoforms by p60(Src).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

A single human myosin light chain kinase gene (MLCK; MYLK).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Regulation of endothelial cell gap formation and barrier dysfunction: role of myosin light chain phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

25 May 2018

Mechanical Stress and Single Nucleotide Variants Regulate Alternative Splicing of the MYLK Gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

13 August 2018

Healthcare disparities in patients with acute respiratory distress syndrome. Toward equity

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13 August 2018

Sphingosine 1-phosphate induces MKP-1 expression via p38 MAPK- and CREB-mediated pathways in airway smooth muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

13 August 2018

Surveillance for certain health behaviors among states and selected local areas - United States, 2008.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

13 August 2018

Novel interaction of cortactin with endothelial cell myosin light chain kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846938

13 August 2018

The Acute Respiratory Distress Syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/29480069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of calmodulin in the first calcium-binding pocket by myosin light chain kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29480069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of endothelial cell myosin light chain kinase by Rho, cortactin, and p60(src)

1 reference

https://pubmed.ncbi.nlm.nih.gov/29480069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-dependent cleavage of myosin light chain kinase (MLCK) is involved in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29480069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A variant of the myosin light chain kinase gene is associated with severe asthma in African Americans

1 reference

https://pubmed.ncbi.nlm.nih.gov/29480069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms in the myosin light chain kinase gene that confer risk of severe sepsis are associated with a lower risk of asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29480069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1177/2045894018764171

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Europe PubMed Central

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18 March 2020

PMC publication ID

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Europe PubMed Central

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18 March 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29480069%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

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