FYVE, RhoGEF and PH domain containing 1 (Q5425457)

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mammalian protein found in Homo sapiens

• FYVE, RhoGEF and PH domain-containing protein 1
• rho/Rac GEF
• FGD1
• zinc finger FYVE domain-containing protein 3
• rho/Rac guanine nucleotide exchange factor FGD1
• faciogenital dysplasia 1 protein

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Language	Label	Description	Also known as
English	FYVE, RhoGEF and PH domain containing 1	mammalian protein found in Homo sapiens	FYVE, RhoGEF and PH domain-containing protein 1 rho/Rac GEF FGD1 zinc finger FYVE domain-containing protein 3 rho/Rac guanine nucleotide exchange factor FGD1 faciogenital dysplasia 1 protein

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P98174

part of

Zinc finger, RING/FYVE/PHD-type

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P98174

Dbl homology (DH) domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P98174

PH-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P98174

pleckstrin homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FGD1-4, C-terminal PH domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FYVE zinc finger, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, FYVE-related, protein family

1 reference

based on heuristic

inferred from protein domain or family

FGD1, N-terminal PH domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Dbl homology (DH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P98174

encoded by

FGD1

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P98174

molecular function

metal ion binding

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

small GTPase binding

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IDA

guanyl-nucleotide exchange factor activity

determination method

IEA

IDA

TAS

3 references

retrieved

5 June 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P98174&geneProductId=UniProtKB:P98174

determination method

TAS

retrieved

5 June 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P98174&geneProductId=UniProtKB:P98174

determination method

IEA

retrieved

5 June 2018

stated in

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P98174&geneProductId=UniProtKB:P98174

determination method

IDA

guanyl-nucleotide exchange factor activity

determination method

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

retrieved

8 April 2019

stated in

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IDA

cell component

cytoplasm

determination method

ISS

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

Golgi apparatus

determination method

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

cell projection

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

cytosol

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

TAS

lamellipodium

determination method

ISS

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

ruffle

determination method

ISS

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

cytoskeleton

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

biological process

regulation of Rho protein signal transduction

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

signal transduction

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

TAS

multicellular organism development

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

TAS

cytoskeleton organization

determination method

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

positive regulation of apoptotic process

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

TAS

regulation of GTPase activity

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IDA

filopodium assembly

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IDA

regulation of small GTPase mediated signal transduction

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

TAS

regulation of cell shape

determination method

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IEA

actin cytoskeleton organization

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

GOA

curator

UniProt

UniProt protein ID

P98174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

IDA

animal organ morphogenesis

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

TAS

G protein-coupled receptor signaling pathway

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98174

determination method

TAS

Gene Atlas image

PBB GE FGD1 204819 at fs.png
732 × 530; 12 KB

0 references

exact match

https://identifiers.org/uniprot:P98174

1 reference

stated in

Identifiers.org

UniProt protein ID

P98174

reference URL

https://registry.identifiers.org/registry/uniprot

http://purl.uniprot.org/uniprot/P98174

1 reference

stated in

Identifiers.org

UniProt protein ID

P98174

reference URL

https://registry.identifiers.org/registry/uniprot

https://www.ncbi.nlm.nih.gov/protein/P98174

1 reference

stated in

Identifiers.org

UniProt protein ID

P98174

reference URL

https://registry.identifiers.org/registry/uniprot

has part(s)

Dbl homology (DH) domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P98174

pleckstrin homology domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P98174

FYVE zinc finger

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P98174

Zinc finger, FYVE-related

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P98174

FGD1-4, C-terminal PH domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P98174

FGD1, N-terminal PH domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P98174

Identifiers

RefSeq protein ID

NP_004454

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2245

UniProt protein ID

P98174

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P98174

Ensembl protein ID

ENSP00000364277

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000364277

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q5425457&oldid=2022907680"