Bone- and cartilage-protective effects of a monoclonal antibody against colony-stimulating factor 1 receptor in experimental arthritis. (Q54369171)

28 May 2018

title

Bone- and cartilage-protective effects of a monoclonal antibody against colony-stimulating factor 1 receptor in experimental arthritis. (English)

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Falk Nimmerjahn

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Georg Schett

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object named as

Georg Schett

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Myew-Ling Toh

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Jean-Yves Bonnefoy

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Nathalie Accart

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Sandrine Cochin

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Sandy Pohle

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Hélène Haegel

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Micael De Meyer

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Christophe Zemmour

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Christine Guillen

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Christine Thioudellet

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Philippe Ancian

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Anja Lux

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Bettina Sehnert

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Reinhard E Voll

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publication date

1 November 2014

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published in

Arthritis & Rheumatology

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volume

66

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issue

11

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page(s)

2989-3000

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The multiple faces of autoimmune-mediated bone loss

cites work

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Colony-stimulating factors in inflammation and autoimmunity.

21 January 2018

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Cytokines in chronic inflammatory arthritis. I. Failure to detect T cell lymphokines (interleukin 2 and interleukin 3) and presence of macrophage colony-stimulating factor (CSF-1) and a novel mast cell growth factor in rheumatoid synovitis

21 January 2018

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Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis

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Interleukin 34 expression is associated with synovitis severity in rheumatoid arthritis patients

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Induction of tumour necrosis factor receptor-expressing macrophages by interleukin-10 and macrophage colony-stimulating factor in rheumatoid arthritis

21 January 2018

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M-CSF potently augments RANKL-induced resorption activation in mature human osteoclasts

21 January 2018

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Interleukin-34 is expressed by giant cell tumours of bone and plays a key role in RANKL-induced osteoclastogenesis

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M-CSF mediates TNF-induced inflammatory osteolysis

21 January 2018

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The colony-stimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion.

21 January 2018

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Expression of Toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritis

21 January 2018

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Transgenic expression of CSF-1 in CSF-1 receptor-expressing cells leads to macrophage activation, osteoporosis, and early death.

21 January 2018

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Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects

21 January 2018

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Incomplete restoration of colony-stimulating factor 1 (CSF-1) function in CSF-1-deficient Csf1op/Csf1op mice by transgenic expression of cell surface CSF-1.

21 January 2018

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M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss.

21 January 2018

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Effects of the cFMS kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine (GW2580) in normal and arthritic rats

21 January 2018

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The orally-active and selective c-Fms tyrosine kinase inhibitor Ki20227 inhibits disease progression in a collagen-induced arthritis mouse model

21 January 2018

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c-Fms-mediated differentiation and priming of monocyte lineage cells play a central role in autoimmune arthritis

21 January 2018

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SB1578, a novel inhibitor of JAK2, FLT3, and c-Fms for the treatment of rheumatoid arthritis.

21 January 2018

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2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

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Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis

21 January 2018

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Overexpression of synoviolin in peripheral blood and synoviocytes from rheumatoid arthritis patients and continued elevation in nonresponders to infliximab treatment

21 January 2018

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A unique anti-CD115 monoclonal antibody which inhibits osteolysis and skews human monocyte differentiation from M2-polarized macrophages toward dendritic cells.

21 January 2018

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Enhancement of adenovirus-mediated gene delivery to rheumatoid arthritis synoviocytes and synovium by fiber modifications: role of arginine-glycine-aspartic acid (RGD)- and non-RGD-binding integrins

21 January 2018

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Grading of chronic synovitis--a histopathological grading system for molecular and diagnostic pathology

21 January 2018

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Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis

21 January 2018

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Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

21 January 2018

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Macrophage colony-stimulating factor stimulates survival and chemotactic behavior in isolated osteoclasts

21 January 2018

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Association between colony-stimulating factor 1 receptor gene polymorphisms and asthma risk

21 January 2018

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Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.

21 January 2018

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Mirimostim (macrophage colony-stimulating factor; M-CSF) improves chemotherapy-induced impaired natural killer cell activity, Th1/Th2 balance, and granulocyte function

21 January 2018

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Collaborative action of M-CSF and CTGF/CCN2 in articular chondrocytes: possible regenerative roles in articular cartilage metabolism

21 January 2018

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Therapeutic effects of anti-CD115 monoclonal antibody in mouse cancer models through dual inhibition of tumor-associated macrophages and osteoclasts

21 January 2018

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Intraperitoneal administration of anti-c-fms monoclonal antibody prevents initial events of atherogenesis but does not reduce the size of advanced lesions in apolipoprotein E-deficient mice

21 January 2018

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An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation

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Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation.

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Identifiers

DOI

10.1002/ART.38624

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28 May 2018

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28 May 2018