Angiotensin-II induces phosphorylation of ERK1/2 and promotes aortic adventitial fibroblasts differentiating into myofibroblasts during aortic dissection formation. (Q54390028)

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English	Angiotensin-II induces phosphorylation of ERK1/2 and promotes aortic adventitial fibroblasts differentiating into myofibroblasts during aortic dissection formation.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

Angiotensin-II induces phosphorylation of ERK1/2 and promotes aortic adventitial fibroblasts differentiating into myofibroblasts during aortic dissection formation. (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

phosphorylation

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author name string

Zhiwei Wang

1

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

Zongli Ren

2

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

Zhipeng Hu

3

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

Xiaoping Hu

4

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

Hao Zhang

5

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

Hongbing Wu

6

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

Min Zhang

7

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

publication date

17 December 2013

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

Journal of Molecular Histology

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

45

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

4

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

401-412

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Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments

1 reference

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Up-regulation of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase were coupled with that of type I procollagen in granulation tissue response after the onset of aortic dissection.

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New insight in aetiopathogenesis of aortic diseases

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Angiotensin II-induced MMP-2 release from endothelial cells is mediated by TNF-alpha

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Hypoxia increases bromodeoxyuridine labeling indices in bovine neonatal pulmonary arteries.

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p38 MAPK contributes to angiotensin II-induced COX-2 expression in aortic fibroblasts from normotensive and hypertensive rats

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Angiotensin II increases tissue-specific inhibitor of metalloproteinase-2 expression in rat aortic smooth muscle cells in vivo: evidence of a pressure-independent effect.

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Natural history, pathogenesis, and etiology of thoracic aortic aneurysms and dissections

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Mouse models of abdominal aortic aneurysms

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Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice

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The myofibroblast in wound healing and fibrocontractive diseases

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The role of extracellular signal-related kinase during abdominal aortic aneurysm formation

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Combinatorial signaling pathways determine fibroblast proliferation and myofibroblast differentiation

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The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease

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The myofibroblast: one function, multiple origins

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Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression

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Collagen and elastin degradation by matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase in aortic dissection.

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Activation of adventitial fibroblasts in the early stage of the aortic transplant vasculopathy in rat.

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Role of oxidative stress in pancreatic inflammation

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Suppression of experimental abdominal aortic aneurysms in the rat by treatment with angiotensin-converting enzyme inhibitors

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Angiotensin II induces MMP-2 in a p47phox-dependent manner

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Genetic basis of thoracic aortic aneurysms and dissections: focus on smooth muscle cell contractile dysfunction

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21 January 2018

Tumor necrosis factor-alpha-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosis

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21 January 2018

NAD(P)H oxidase-derived reactive oxygen species regulate angiotensin-II induced adventitial fibroblast phenotypic differentiation

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Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts.

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An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice.

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21 January 2018

Role of extracellular signal-regulated kinases in angiotensin II-stimulated contraction of smooth muscle cells from human resistance arteries.

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21 January 2018

Angiotensin II and endothelin-1 regulate MAP kinases through different redox-dependent mechanisms in human vascular smooth muscle cells

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21 January 2018

Possible roles of angiotensin II-forming enzymes, angiotensin converting enzyme and chymase-like enzyme, in the human aneurysmal aorta

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21 January 2018

Adrenomedullin induces matrix metalloproteinase-2 activity in rat aortic adventitial fibroblasts

1 reference

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21 January 2018

Adventitial fibroblasts in vascular structure and function: the role of oxidative stress and beyond

1 reference

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21 January 2018

Angiotensin II signalling and calcineurin in cardiac fibroblasts: differential effects of calcineurin inhibitors FK506 and cyclosporine A.

1 reference

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21 January 2018

Angiotensin II downregulates catalase expression and activity in vascular adventitial fibroblasts through an AT1R/ERK1/2-dependent pathway

1 reference

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Vascular myofibroblasts. Lessons from coronary repair and remodeling

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Adventitial fibroblasts are activated in the early stages of atherosclerosis in the apolipoprotein E knockout mouse

1 reference

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Localisation of mRNA for JE/MCP-1 and its receptor CCR2 in atherosclerotic lesions of the ApoE knockout mouse

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Adventitial myofibroblasts contribute to neointimal formation in injured porcine coronary arteries

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Identification of a potential role for the adventitia in vascular lesion formation after balloon overstretch injury of porcine coronary arteries

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Angiotensin II type 2 receptor mediates vascular smooth muscle cell apoptosis in cystic medial degeneration associated with Marfan's syndrome

1 reference

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Abdominal aortic aneurysm

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Dissecting aneurysm of the aorta: a review of 505 cases.

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Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm

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Increased migration of vascular adventitial fibroblasts from spontaneously hypertensive rats

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Collagen gel overlay induces apoptosis of polarized cells in cultures: disoriented cell death

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Increased collagen deposition and elevated expression of connective tissue growth factor in human thoracic aortic dissection

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12 December 2020

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Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms

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The adventitia and atherogenesis: removal initiates intimal proliferation in the rabbit which regresses on generation of a 'neoadventitia'

1 reference

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Possible involvement of myofibroblast in the development of inflammatory aortic aneurysm

1 reference

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Salt-sensitive aortic aneurysm and rupture in hypertensive transgenic mice that overproduce angiotensin II

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Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

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Perivascular responses after angioplasty which may contribute to postangioplasty restenosis: a role for circulating myofibroblast precursors?

1 reference

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Identifiers

10.1007/S10735-013-9558-8

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/24343777

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