Phorbol esters from Jatropha meal triggered apoptosis, activated PKC-δ, caspase-3 proteins and down-regulated the proto-oncogenes in MCF-7 and HeLa cancer cell lines. (Q54485008)

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English	Phorbol esters from Jatropha meal triggered apoptosis, activated PKC-δ, caspase-3 proteins and down-regulated the proto-oncogenes in MCF-7 and HeLa cancer cell lines.	scientific article

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12 February 2020

Phorbol esters from Jatropha meal triggered apoptosis, activated PKC-δ, caspase-3 proteins and down-regulated the proto-oncogenes in MCF-7 and HeLa cancer cell lines (English)

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12 February 2020

Ehsan Oskoueian

1

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12 February 2020

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Norhani Abdullah

2

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12 February 2020

Syahida Ahmad

3

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10 September 2012

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12 February 2020

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12 February 2020

17

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12 February 2020

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12 February 2020

10816-10830

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12 February 2020

copyright license

Creative Commons Attribution 4.0 International

10 September 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

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Toxicological evaluation of some Malaysian locally processed raw food products

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel 12-deoxy-16-hydroxyphorbol diesters isolated from the seed oil of Jatropha curcas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic biology of Jatropha curcas: a mini review

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic Activity of Crude Extracts as well as of Pure Components from Jatropha Species, Plants Used Extensively in African Traditional Medicine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effects of 12-O-tetradecanoylphorbol-13-acetate alone or in combination with all-trans retinoic acid on the growth of cultured human pancreas cancer cells and pancreas tumor xenografts in immunodeficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downregulation of c-Jun expression by transcription factor C/EBPalpha is critical for granulocytic lineage commitment

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdelta

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase activation during phorbol ester-induced apoptosis requires ROCK-dependent myosin-mediated contraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of c-jun protein in proliferation and apoptosis of the endometrium throughout the menstrual cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective extraction of fragmented DNA from apoptotic cells for analysis by gel electrophoresis and identification of apoptotic cells by flow cytometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioactive compounds and biological activities of Jatropha curcas L. kernel meal extract.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol esters: structure, biological activity, and toxicity in animals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C isozymes as potential targets for anticancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nutritional, biochemical, and pharmaceutical potential of proteins and peptides from jatropha: review

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen receptor alpha, fos-related antigen-2, and c-Jun coordinately regulate human UDP glucuronosyltransferase 2B15 and 2B17 expression in response to 17beta-estradiol in MCF-7 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cochaperone p23 differentially regulates estrogen receptor target genes and promotes tumor cell adhesion and invasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol ester-induced apoptosis is accompanied by NGFI-A and c-fos activation in androgen-sensitive prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microgravity modifies protein kinase C isoform translocation in the human monocytic cell line U937 and human peripheral blood T-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A protein kinase C/protein kinase D pathway protects LNCaP prostate cancer cells from phorbol ester-induced apoptosis by promoting ERK1/2 and NF-{kappa}B activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advances in flavonoid research since 1992.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity of Jatropha curcas phorbol esters in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting protein kinase C and "non-kinase" phorbol ester receptors: emerging concepts and therapeutic implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic action of phorbol esters on human pancreatic cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C activation by PMA rapidly induces apoptosis through caspase-3/CPP32 and serine protease(s) in a gastric cancer cell line.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3-dependent protein kinase C delta activity is required for the progression of Ginsenoside-Rh2-induced apoptosis in SK-HEP-1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C-beta, fibronectin, alpha(5)beta(1)-integrin, and tumor necrosis factor-alpha are required for phorbol diester-induced apoptosis in human myeloid leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22964499

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/MOLECULES170910816

1 reference

Europe PubMed Central

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12 February 2020

1 reference

Europe PubMed Central

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12 February 2020

1 reference

Europe PubMed Central

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12 February 2020

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