Tumour suppressor p16(INK4a) - anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model. (Q54486460)

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English	Tumour suppressor p16(INK4a) - anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model.	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

Tumour suppressor p16(INK4a) - anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model. (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

pancreatic carcinoma

1 reference

based on heuristic

inferred from title

5

1 reference

Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

7

1 reference

Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

Hans-Joachim Gabius

8

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Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

author name string

Maho Amano

1

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Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

Hanna Eriksson

2

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Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

Joachim C Manning

3

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Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

Katharina M Detjen

4

1 reference

Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

Shin-Ichiro Nishimura

6

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PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

language of work or name

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publication date

1 November 2012

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Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

1 reference

Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

279

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Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

21

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Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

4062-4080

1 reference

Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

The Significance of Glycosylated Proteins

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21 January 2018

From lectin structure to functional glycomics: principles of the sugar code.

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21 January 2018

The c-Ha-ras oncogene induces increased expression of beta-galactoside alpha-2, 6-sialyltransferase in rat fibroblast (FR3T3) cells.

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21 January 2018

Ras oncogene directs expression of a differentially sialylated, functionally altered β1 integrin

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21 January 2018

Compensation of loss of protein function in microsatellite-unstable colon cancer cells (HCT116): a gene-dependent effect on the cell surface glycan profile.

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21 January 2018

Tumor suppressor p16INK4a--modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells

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21 January 2018

Hypersialylation of beta1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility

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21 January 2018

Tumor cell migration and invasion are regulated by expression of variant integrin glycoforms

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Plasma glycoprotein profiling for colorectal cancer biomarker identification by lectin glycoarray and lectin blot.

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Hyposialylation of integrins stimulates the activity of myeloid fibronectin receptors

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A novel function for the tumor suppressor p16(INK4a): induction of anoikis via upregulation of the alpha(5)beta(1) fibronectin receptor

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21 January 2018

Tumor suppressor p16 INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model.

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21 January 2018

Dimeric galectin-1 binds with high affinity to alpha2,3-sialylated and non-sialylated terminal N-acetyllactosamine units on surface-bound extended glycans.

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21 January 2018

N- and O-glycans modulate galectin-1 binding, CD45 signaling, and T cell death

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The ST6Gal I sialyltransferase selectively modifies N-glycans on CD45 to negatively regulate galectin-1-induced CD45 clustering, phosphatase modulation, and T cell death

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Glycoblotting-assisted O-glycomics: ammonium carbamate allows for highly efficient o-glycan release from glycoproteins

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Toward automated glycan analysis

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Quantitative membrane proteomics applying narrow range peptide isoelectric focusing for studies of small cell lung cancer resistance mechanisms

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Branch-specific sialylation of IgG-Fc glycans by ST6Gal-I.

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21 January 2018

A mathematical model of sialylation of N-linked oligosaccharides in the trans-Golgi network.

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21 January 2018

Metabolic glycoengineering: sialic acid and beyond

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UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation

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21 January 2018

Galectin-1 sensitizes carcinoma cells to anoikis via the fibronectin receptor α5β1-integrin.

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21 January 2018

Sialylation is essential for early development in mice

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21 January 2018

Mutation in the key enzyme of sialic acid biosynthesis causes severe glomerular proteinuria and is rescued by N-acetylmannosamine

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21 January 2018

Prophylactic treatment with sialic acid metabolites precludes the development of the myopathic phenotype in the DMRV-hIBM mouse model

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21 January 2018

Lessons from GNE-deficient embryonic stem cells: sialic acid biosynthesis is involved in proliferation and gene expression

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Loss of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) induces apoptotic processes in pancreatic carcinoma cells

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21 January 2018

Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents

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8-plex quantitation of changes in cerebrospinal fluid protein expression in subjects undergoing intravenous immunoglobulin treatment for Alzheimer's disease

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Observed peptide pI and retention time shifts as a result of post-translational modifications in multidimensional separations using narrow-range IPG-IEF.

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21 January 2018

Prediction of three different isoforms of the human UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase.

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Identification, tissue distribution, and molecular modeling of novel human isoforms of the key enzyme in sialic acid synthesis, UDP-GlcNAc 2-epimerase/ManNAc kinase

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21 January 2018

Purification and characterization of N-acetylneuraminic acid-9-phosphate synthase from rat liver

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21 January 2018

THE FEEDBACK CONTROL OF SUGAR NUCLEOTIDE BIOSYNTHESIS IN LIVER

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21 January 2018

Purification and properties of UDP-N-acetylglucosamine 2'-epimerase from rat liver

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21 January 2018

A bifunctional enzyme catalyzes the first two steps in N-acetylneuraminic acid biosynthesis of rat liver. Purification and characterization of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12001

21 January 2018

Activity-structure correlations in divergent lectin evolution: fine specificity of chicken galectin CG-14 and computational analysis of flexible ligand docking for CG-14 and the closely related CG-16.

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21 January 2018

Human galectin-3 (Mac-2 antigen): defining molecular switches of affinity to natural glycoproteins, structural and dynamic aspects of glycan binding by flexible ligand docking and putative regulatory sequences in the proximal promoter region

1 reference

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Expression of sialyl-Tn epitopes on beta1 integrin alters epithelial cell phenotype, proliferation and haptotaxis.

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Purification and characterization of a Neu5Acalpha2-6Galbeta1-4Glc/GlcNAc-specific lectin from the fruiting body of the polypore mushroom Polyporus squamosus

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Rapid determination of the binding affinity and specificity of the mushroom Polyporus squamosus lectin using frontal affinity chromatography coupled to electrospray mass spectrometry

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Structure and binding analysis of Polyporus squamosus lectin in complex with the Neu5Ac 2-6Gal 1-4GlcNAc human-type influenza receptor

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Negative regulation of neuroblastoma cell growth by carbohydrate-dependent surface binding of galectin-1 and functional divergence from galectin-3.

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Cross-linking of GM1 ganglioside by galectin-1 mediates regulatory T cell activity involving TRPC5 channel activation: possible role in suppressing experimental autoimmune encephalomyelitis.

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Beyond glycoproteins as galectin counterreceptors: tumor-effector T cell growth control via ganglioside GM1 [corrected].

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Galectin-1 interacts with the {alpha}5{beta}1 fibronectin receptor to restrict carcinoma cell growth via induction of p21 and p27.

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Galectin-1 is highly expressed in human gliomas with relevance for modulation of invasion of tumor astrocytes into the brain parenchyma

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Galectin-1 is a novel functional receptor for tissue plasminogen activator in pancreatic cancer.

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21 January 2018

The expression of CMP-NeuAc: Gal beta 1,4GlcNAc alpha 2,6 sialyltransferase [EC 2.4.99.1] and glycoproteins bearing alpha 2,6-linked sialic acids in human brain tumours.

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21 January 2018

The expression of Gal beta 1,4GlcNAc alpha 2,6 sialyltransferase and alpha 2,6-linked sialoglycoconjugates in human brain tumors

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Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1

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Klotho: a novel regulator of calcium and phosphorus homeostasis

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O-glycosylation regulates LNCaP prostate cancer cell susceptibility to apoptosis induced by galectin-1.

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Roles for UDP-GlcNAc 2-epimerase/ManNAc 6-kinase outside of sialic acid biosynthesis: modulation of sialyltransferase and BiP expression, GM3 and GD3 biosynthesis, proliferation, and apoptosis, and ERK1/2 phosphorylation.

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Carbohydrate-carbohydrate binding of ganglioside to integrin alpha(5) modulates alpha(5)beta(1) function.

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Ganglioside GM1 deficiency in effector T cells from NOD mice induces resistance to regulatory T-cell suppression

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Galectin-7 (PIG1) exhibits pro-apoptotic function through JNK activation and mitochondrial cytochrome c release

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Phosphorylated human galectin-3: facile large-scale preparation of active lectin and detection of structural changes by CD spectroscopy.

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Unique chicken tandem-repeat-type galectin: implications of alternative splicing and a distinct expression profile compared to those of the three proto-type proteins

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A bifunctional enzyme catalyzes the first two steps in N-acetylneuraminic acid biosynthesis of rat liver. Molecular cloning and functional expression of UDP-N-acetyl-glucosamine 2-epimerase/N-acetylmannosamine kinase

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Threshold in stage-specific embryonic glycotypes uncovered by a full portrait of dynamic N-glycan expression during cell differentiation

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Universal sample preparation method for proteome analysis

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Identifiers

10.1111/FEBS.12001

1 reference

Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 May 2018

http://europepmc.org/abstract/MED/22943525

ResearchGate publication ID

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