Impaired JAK2-induced activation of STAT3 in failing human myocytes. (Q54501635)

30 May 2018

title

Impaired JAK2-induced activation of STAT3 in failing human myocytes. (English)

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30 May 2018

author

Giuseppe Faggian

6

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Alessandra Modesti

object named as

Alessandra Modesti

4

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Pietro Amedeo Modesti

object named as

Pietro Amedeo Modesti

8

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author name string

Giulia Elisa Cambi

1

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30 May 2018

Gianluca Lucchese

2

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Mah Mc Harol Djeokeng

3

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Tania Fiaschi

5

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Guido Sani

7

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30 May 2018

publication date

26 June 2012

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30 May 2018

published in

Molecular BioSystems

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30 May 2018

volume

8

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issue

9

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page(s)

2351-2359

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30 May 2018

Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age

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Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury

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JAK redux: a second look at the regulation and role of JAKs in the heart

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Role of angiotensin II in activation of the JAK/STAT pathway induced by acute pressure overload in the rat heart

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Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

21 January 2018

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Hyperglycemia activates JAK2 signaling pathway in human failing myocytes via angiotensin II-mediated oxidative stress

21 January 2018

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IFN-type-I-mediated signaling is regulated by modulation of STAT2 nuclear export

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Stat1 and Stat2 but not Stat3 arbitrate contradictory growth signals elicited by alpha/beta interferon in T lymphocytes.

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JAK/STAT signaling is associated with cardiac dysfunction during ischemia and reperfusion

21 January 2018

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Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-alpha

21 January 2018

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Identification of novel direct Stat3 target genes for control of growth and differentiation

21 January 2018

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Erythropoietin can induce the expression of bcl-x(L) through Stat5 in erythropoietin-dependent progenitor cell lines

21 January 2018

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Cardiac angiotensin II formation in the clinical course of heart failure and its relationship with left ventricular function

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Cell type-specific angiotensin II-evoked signal transduction pathways: critical roles of Gbetagamma subunit, Src family, and Ras in cardiac fibroblasts

21 January 2018

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Angiotensin II activates signal transducer and activators of transcription 3 via Rac1 in atrial myocytes and fibroblasts: implication for the therapeutic effect of statin in atrial structural remodeling

21 January 2018

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AT1 blockade prevents glucose-induced cardiac dysfunction in ventricular myocytes: role of the AT1 receptor and NADPH oxidase

21 January 2018

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Angiotensin II activation of the JAK/STAT pathway in mesangial cells is altered by high glucose.

21 January 2018

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Can the protective actions of JAK-STAT in the heart be exploited therapeutically? Parsing the regulation of interleukin-6-type cytokine signaling

21 January 2018

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Hyperglycemia activates p53 and p53-regulated genes leading to myocyte cell death.

21 January 2018

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Induction of apoptosis and Fas receptor/Fas ligand expression by ischemia/reperfusion in cardiac myocytes requires serine 727 of the STAT-1 transcription factor but not tyrosine 701.

21 January 2018

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Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression

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A road map for those who don't know JAK-STAT

21 January 2018

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Signal transduction and activator of transcription (STAT) protein-dependent activation of angiotensinogen promoter: a cellular signal for hypertrophy in cardiac muscle

21 January 2018

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Resveratrol downregulates Akt/GSK and ERK signalling pathways in OVCAR-3 ovarian cancer cells

21 January 2018

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Why have antioxidants failed in clinical trials?

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New insights about vitamin D and cardiovascular disease: a narrative review

21 January 2018

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Impaired angiotensin II–extracellular signal-regulated kinase signaling in failing human ventricular myocytes

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1039/C2MB25120E

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30 May 2018

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30 May 2018