Genetic characterization of mesenchymal, clear cell, and dedifferentiated chondrosarcoma. (Q54506099)

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3 February 2020

title

Genetic characterization of mesenchymal, clear cell, and dedifferentiated chondrosarcoma (English)

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3 February 2020

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5

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3 February 2020

Karoly Szuhai

6

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3 February 2020

Danielle de Jong

2

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3 February 2020

Judith Bovée

7

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3 February 2020

author name string

Danielle Meijer

1

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3 February 2020

Twinkal C Pansuriya

3

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3 February 2020

Brendy E van den Akker

4

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publication date

4 June 2012

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Genes, Chromosomes and Cancer

3 February 2020

published in

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volume

51

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issue

10

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3 February 2020

page(s)

899-909

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IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours

3 February 2020

cites work

1 reference

Alterations in the regulatory pathway involving p16, pRb and cdk4 in human chondrosarcoma.

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Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

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Secondary peripheral chondrosarcoma evolving from osteochondroma as a result of outgrowth of cells with functional EXT

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Opening the archives for state of the art tumour genetic research: sample processing for array-CGH using decalcified, formalin-fixed, paraffin-embedded tissue-derived DNA samples

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Loss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation.

21 January 2018

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Genomic profiling of chondrosarcoma: chromosomal patterns in central and peripheral tumors.

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Germline p16 mutations in familial melanoma

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A cell cycle regulator potentially involved in genesis of many tumor types

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Expression of aromatase and estrogen receptor alpha in chondrosarcoma, but no beneficial effect of inhibiting estrogen signaling both in vitro and in vivo

21 January 2018

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Small deletions but not methylation underlie CDKN2A/p16 loss of expression in conventional osteosarcoma.

21 January 2018

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CDKN2A gene deletions and loss of p16 expression occur in osteosarcomas that lack RB alterations

21 January 2018

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Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome

21 January 2018

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Cell cycle/apoptosis molecule expression correlates with imatinib response in patients with advanced gastrointestinal stromal tumors.

21 January 2018

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Genetic and epigenetic alterations in tumor progression in a dedifferentiated chondrosarcoma.

21 January 2018

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Array-comparative genomic hybridization of central chondrosarcoma: identification of ribosomal protein S6 and cyclin-dependent kinase 4 as candidate target genes for genomic aberrations.

21 January 2018

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CanGEM: mining gene copy number changes in cancer

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The RB and p53 pathways in cancer

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Correlation between clinicopathological features and karyotype in 100 cartilaginous and chordoid tumours. A report from the Chromosomes and Morphology (CHAMP) Collaborative Study Group

21 January 2018

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Molecular analysis of the INK4A/INK4A-ARF gene locus in conventional (central) chondrosarcomas and enchondromas: indication of an important gene for tumour progression

21 January 2018

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MLPAinter for MLPA interpretation: an integrated approach for the analysis, visualisation and data management of Multiplex Ligation-dependent Probe Amplification

21 January 2018

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Weighted clustering of called array CGH data

21 January 2018

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Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon-level expression data

21 January 2018

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EWSR1-CREB1 and EWSR1-ATF1 Fusion Genes in Angiomatoid Fibrous Histiocytoma

21 January 2018

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Changes of the p16 gene but not the p53 gene in human chondrosarcoma tissues

21 January 2018

1 reference

7 January 2021

Clear cell chondrosarcoma of bone. Observations in 47 cases

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7 January 2021

Molecular genetic characterization of both components of a dedifferentiated chondrosarcoma, with implications for its histogenesis

1 reference

7 January 2021

Chromosome 9 alterations and trisomy 22 in central chondrosarcoma: a cytogenetic and DNA flow cytometric analysis of chondrosarcoma subtypes

1 reference

7 January 2021

Rates of p16 (MTS1) mutations in primary tumors with 9p loss

1 reference

7 January 2021

p53 expression and DNA ploidy of cartilage lesions

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7 January 2021

IDH1 mutations are not found in cartilaginous tumours other than central and periosteal chondrosarcomas and enchondromas

1 reference

7 January 2021

Prognostic factors in chondrosarcoma of bone: a clinicopathologic analysis with emphasis on histologic grading

1 reference

7 January 2021

Mutation of p53 with loss of heterozygosity in the osteosarcomatous component of a dedifferentiated chondrosarcoma

1 reference

7 January 2021

Mesenchymal chondrosarcoma. A clinicopathologic analysis of 35 patients with emphasis on treatment

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7 January 2021

Cytogenetic findings in clear cell chondrosarcoma

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7 January 2021

Clear cell chondrosarcoma of bone. A report of 8 cases

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7 January 2021

Urinary excretion of C5b-9 reflects disease activity in passive Heymann nephritis

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7 January 2021

Dedifferentiated peripheral chondrosarcomas: regulation of EXT-downstream molecules and differentiation-related genes

1 reference

7 January 2021