The dark side of a success story: microRNAs of the C19MC cluster in human tumours. (Q54526480)

30 May 2018

title

The dark side of a success story: microRNAs of the C19MC cluster in human tumours. (English)

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30 May 2018

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Inga Flor

1

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30 May 2018

Jörn Bullerdiek

series ordinal

2

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30 May 2018

publication date

30 April 2012

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30 May 2018

published in

Journal of Pathology

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30 May 2018

volume

227

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30 May 2018

issue

3

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30 May 2018

page(s)

270-274

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30 May 2018

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Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

21 January 2018

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Identification of mammalian microRNA host genes and transcription units

21 January 2018

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Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

21 January 2018

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The DNA sequence and biology of human chromosome 19

21 January 2018

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Identification of hundreds of conserved and nonconserved human microRNAs

21 January 2018

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Molecular Evolution of a Primate-Specific microRNA Family

21 January 2018

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Evidence for co-evolution between human microRNAs and Alu-repeats

21 January 2018

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C19MC microRNAs are processed from introns of large Pol-II, non-protein-coding transcripts

21 January 2018

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Epigenetic control of the expression of a primate-specific microRNA cluster in human cancer cells

21 January 2018

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The primate-specific microRNA gene cluster (C19MC) is imprinted in the placenta

21 January 2018

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The two stem cell microRNA gene clusters C19MC and miR-371-3 are activated by specific chromosomal rearrangements in a subgroup of thyroid adenomas

21 January 2018

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In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2.

21 January 2018

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Characterization of microRNA expression profiles in normal human tissues

21 January 2018

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A mammalian microRNA expression atlas based on small RNA library sequencing

21 January 2018

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MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries

21 January 2018

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Comprehensive microRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence

21 January 2018

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Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells

21 January 2018

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MicroRNA and gene expression patterns in the differentiation of human embryonic stem cells

21 January 2018

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Evolutionary emergence of microRNAs in human embryonic stem cells

21 January 2018

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mir-17-92, a cluster of miRNAs in the midst of the cancer network

21 January 2018

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Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

21 January 2018

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miR-15 and miR-16 induce apoptosis by targeting BCL2

21 January 2018

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The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

21 January 2018

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MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-κB and TGF-β signaling pathways.

21 January 2018

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MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence

21 January 2018

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miR-519 suppresses tumor growth by reducing HuR levels

21 January 2018

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Deregulation of miR-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumours

21 January 2018

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Diagnostic and prognostic microRNAs in stage II colon cancer.

21 January 2018

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Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors

21 January 2018

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Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells.

21 January 2018

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Genetic alterations in microRNAs in medulloblastomas

21 January 2018

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Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3' untranslated region

21 January 2018

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Three dysregulated miRNAs control kallikrein 10 expression and cell proliferation in ovarian cancer

21 January 2018

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Down-regulation of Wee1 kinase by a specific subset of microRNA in human sporadic pituitary adenomas

21 January 2018

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Novel genomic amplification targeting the microRNA cluster at 19q13.42 in a pediatric embryonal tumor with abundant neuropil and true rosettes.

21 January 2018

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MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a

21 January 2018

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Functional screening identifies a microRNA, miR-491 that induces apoptosis by targeting Bcl-X(L) in colorectal cancer cells

21 January 2018

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miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels

21 January 2018

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miR-221 overexpression contributes to liver tumorigenesis

21 January 2018

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Escape from hsa-miR-519c enables drug-resistant cells to maintain high expression of ABCG2.

21 January 2018

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MicroRNA-519c suppresses hypoxia-inducible factor-1alpha expression and tumor angiogenesis

21 January 2018

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Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328, -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells

21 January 2018

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MicroRNA-519d targets MKi67 and suppresses cell growth in the hepatocellular carcinoma cell line QGY-7703.

21 January 2018

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miRNA-520b and miR-520e sensitize breast cancer cells to complement attack via directly targeting 3'UTR of CD46.

21 January 2018

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miR-520b regulates migration of breast cancer cells by targeting hepatitis B X-interacting protein and interleukin-8

21 January 2018

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miR-520c and miR-373 upregulate MMP9 expression by targeting mTOR and SIRT1, and activate the Ras/Raf/MEK/Erk signaling pathway and NF-κB factor in human fibrosarcoma cells

21 January 2018

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MicroRNA-520e suppresses growth of hepatoma cells by targeting the NF-κB-inducing kinase (NIK).

21 January 2018

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hsa-miR-520h downregulates ABCG2 in pancreatic cancer cells to inhibit migration, invasion, and side populations

21 January 2018

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Downregulation of microRNA miR-520h by E1A contributes to anticancer activity

21 January 2018

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Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.4014

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30 May 2018

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30 May 2018