A new turn in Rho GTPase activation by Escherichia coli cytotoxic necrotizing factors. (Q54526518)

30 May 2018

title

A new turn in Rho GTPase activation by Escherichia coli cytotoxic necrotizing factors. (English)

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30 May 2018

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Klaus Aktories

1

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30 May 2018

Gudula Schmidt

series ordinal

2

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30 May 2018

publication date

1 April 2003

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30 May 2018

published in

Trends in Microbiology

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30 May 2018

volume

11

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30 May 2018

issue

4

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30 May 2018

page(s)

152-155

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30 May 2018

Rho GTPases in cell biology

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Mutation of the gene encoding cytotoxic necrotizing factor type 1 (cnf(1)) attenuates the virulence of uropathogenic Escherichia coli

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The Rho-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity. Cysteine 866 and histidine 881 are essential for enzyme activity

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Mutation of specific acidic residues of the CNF1 T domain into lysine alters cell membrane translocation of the toxin

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7 January 2021

10.1016/S0966-842X(03)00042-8

Identifiers

DOI

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30 May 2018

PubMed ID

12706988

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30 May 2018