The role of cyclooxygenase-2 (COX-2) in two different morphological stages of intestinal polyps in APC(Delta474) knockout mice. (Q54540726)

31 May 2018

title

The role of cyclooxygenase-2 (COX-2) in two different morphological stages of intestinal polyps in APC(Delta474) knockout mice. (English)

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31 May 2018

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Ken-ichi Sunayama

1

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31 May 2018

Hiroyuki Konno

2

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31 May 2018

Toshio Nakamura

3

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31 May 2018

Hidehumi Kashiwabara

4

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31 May 2018

Tsuyoshi Shoji

5

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31 May 2018

Toshihiro Tsuneyoshi

6

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31 May 2018

Satoshi Nakamura

7

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31 May 2018

language of work or name

English

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publication date

1 August 2002

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31 May 2018

published in

Carcinogenesis

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31 May 2018

volume

23

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issue

8

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31 May 2018

page(s)

1351-1359

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31 May 2018

A hypothesis: nonsteroidal anti-inflammatory drugs reduce the incidence of large-bowel cancer.

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Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

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Suppression of polypogenesis in a new mouse strain with a truncated Apc(Delta474) by a novel COX-2 inhibitor, JTE-522

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Localization of cyclooxygenase-2 in human sporadic colorectal adenomas

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Cyclooxygenase 2 is up-regulated and localized to macrophages in the intestine of Min mice.

21 January 2018

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Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice

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Piroxicam and acarbose as chemopreventive agents for spontaneous intestinal adenomas in APC gene 1309 knockout mice

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Genetic alterations during colorectal-tumor development

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APC mutations occur early during colorectal tumorigenesis

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Cyclooxygenase regulates angiogenesis induced by colon cancer cells

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A selective cyclooxygenase-2 inhibitor suppresses tumor growth in nude mouse xenografted with human head and neck squamous carcinoma cells

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Apoptosis induced by NS-398, a selective cyclooxygenase-2 inhibitor, in human colorectal cancer cell lines.

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NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis.

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High expression of cyclooxygenase-2 in macrophages of human colonic adenoma.

21 January 2018

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The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/CARCIN/23.8.1351

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31 May 2018

1 reference

31 May 2018