The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. (Q54558041)

31 May 2018

title

The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. (English)

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13

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author name string

Youcun Qian

1

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Caini Liu

2

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Justin Hartupee

3

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Cengiz Zubeyir Altuntas

4

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Muhammet Fatih Gulen

5

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Daniel Jane-Wit

6

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Jianhua Xiao

7

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Yi Lu

8

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Natalia Giltiay

9

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Jinbo Liu

10

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Tomasz Kordula

11

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Qi-Wei Zhang

12

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Shadi Swaidani

14

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Mark Aronica

15

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Vincent K Tuohy

16

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Thomas Hamilton

17

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Xiaoxia Li

18

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language of work or name

English

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publication date

4 February 2007

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published in

Nature Immunology

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volume

8

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issue

3

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page(s)

247-256

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Interleukin-17 family members and inflammation

cites work

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7 January 2021

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

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7 January 2021

Transforming growth factor-beta induces development of the T(H)17 lineage

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7 January 2021

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

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7 January 2021

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

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7 January 2021

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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7 January 2021

Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses

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7 January 2021

The IL-23/IL-17 axis in inflammation

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7 January 2021

Cutting edge: interleukin 17 signals through a heteromeric receptor complex

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7 January 2021

Interleukin-17 stimulates inducible nitric oxide synthase activation in rodent astrocytes.

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IL-17A promotes the growth of airway epithelial cells through ERK-dependent signaling pathway

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7 January 2021

The STIR-domain superfamily in signal transduction, development and immunity

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7 January 2021

Molecular characterization of the human interleukin (IL)-17 receptor

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7 January 2021

Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transduction

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7 January 2021

Act1, an NF-kappa B-activating protein

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7 January 2021

CIKS, a connection to Ikappa B kinase and stress-activated protein kinase

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7 January 2021

Role of NF kappa B activator Act1 in CD40-mediated signaling in epithelial cells

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7 January 2021

Act1, a negative regulator in CD40- and BAFF-mediated B cell survival

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7 January 2021

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

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7 January 2021

Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis

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7 January 2021

Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop

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7 January 2021

Functional Cooperation between Interleukin-17 and Tumor Necrosis Factor-α Is Mediated by CCAAT/Enhancer-binding Protein Family Members

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7 January 2021

An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization.

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7 January 2021

Antigen presentation in autoimmunity and CNS inflammation: how T lymphocytes recognize the brain.

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7 January 2021

Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research.

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7 January 2021

Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis.

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7 January 2021

Immune function of astrocytes

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7 January 2021

Critical role of IL-17 receptor signaling in acute TNBS-induced colitis

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7 January 2021

IFN regulatory factor-1 is required for the up-regulation of the CD40-NF-kappa B activator 1 axis during airway inflammation

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7 January 2021

Interleukin-17 is a potent immuno-modulator and regulator of normal human intestinal epithelial cell growth.

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7 January 2021

Expression of conditional cre recombinase in epithelial tissues of transgenic mice

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7 January 2021

Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense

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7 January 2021

IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis.

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7 January 2021

Identification of common transcriptional regulatory elements in interleukin-17 target genes

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7 January 2021

Essential function for the kinase TAK1 in innate and adaptive immune responses.

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7 January 2021

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

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7 January 2021

Constitutive expression of the B7h ligand for inducible costimulator on naive B cells is extinguished after activation by distinct B cell receptor and interleukin 4 receptor-mediated pathways and can be rescued by CD40 signaling

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7 January 2021

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

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7 January 2021

Oncostatin M and the interleukin-6 and soluble interleukin-6 receptor complex regulate alpha1-antichymotrypsin expression in human cortical astrocytes.

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7 January 2021

Identifiers

DOI

10.1038/NI1439

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31 May 2018

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