TNF-alpha induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-kappaB/p300 binding in human tracheal smooth muscle cells. (Q54568076)

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English	TNF-alpha induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-kappaB/p300 binding in human tracheal smooth muscle cells.	scientific article

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Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/17158602

TNF-alpha induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-kappaB/p300 binding in human tracheal smooth muscle cells. (English)

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1 June 2018

http://europepmc.org/abstract/MED/17158602

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Chiang-Wen Lee

1

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1 June 2018

http://europepmc.org/abstract/MED/17158602

Chih-Chung Lin

2

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1 June 2018

http://europepmc.org/abstract/MED/17158602

Wei-Ning Lin

3

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1 June 2018

http://europepmc.org/abstract/MED/17158602

Kao-Chih Liang

4

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1 June 2018

http://europepmc.org/abstract/MED/17158602

Shue-Feng Luo

5

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1 June 2018

http://europepmc.org/abstract/MED/17158602

Chow-Bin Wu

6

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1 June 2018

http://europepmc.org/abstract/MED/17158602

Shyi-Wu Wang

7

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1 June 2018

http://europepmc.org/abstract/MED/17158602

Chuen-Mao Yang

8

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1 June 2018

http://europepmc.org/abstract/MED/17158602

publication date

8 December 2006

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1 June 2018

http://europepmc.org/abstract/MED/17158602

American Journal of Physiology - Lung Cellular and Molecular Physiology

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http://europepmc.org/abstract/MED/17158602

292

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http://europepmc.org/abstract/MED/17158602

L799-812

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3

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http://europepmc.org/abstract/MED/17158602

Phosphorylation by p44 MAP Kinase/ERK1 stimulates CBP histone acetyl transferase activity in vitro

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Matrix metalloproteinase-9 in lung remodeling

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Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activation

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Intracellular signalings underlying bradykinin-induced matrix metalloproteinase-9 expression in rat brain astrocyte-1.

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Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity

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c-Src-dependent tyrosine phosphorylation of IKKbeta is involved in tumor necrosis factor-alpha-induced intercellular adhesion molecule-1 expression

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Tyrosine Phosphorylation of I-κB Kinase α/β by Protein Kinase C-Dependent c-Src Activation Is Involved in TNF-α-Induced Cyclooxygenase-2 Expression

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Phosphorylation of CBP mediates transcriptional activation by neural activity and CaM kinase IV.

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Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor

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The role of PI3K in immune cells

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c-Src is activated by the epidermal growth factor receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cells

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VCAM-1 activates phosphatidylinositol 3-kinase and induces p120Cbl phosphorylation in human airway smooth muscle cells

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Airway epithelial cell migration dynamics. MMP-9 role in cell-extracellular matrix remodeling

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Tumor necrosis factor-alpha-induced cyclooxygenase-2 expression in human tracheal smooth muscle cells: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kappaB.

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21 January 2018

Coordination of cell signaling, chromatin remodeling, histone modifications, and regulator recruitment in human matrix metalloproteinase 9 gene transcription

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Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

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ERK1/2 mediates TNF-alpha-induced matrix metalloproteinase-9 expression in human vascular smooth muscle cells via the regulation of NF-kappaB and AP-1: Involvement of the ras dependent pathway

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

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Transcriptional regulation of cyclooxygenase 2 by bradykinin and interleukin-1beta in human airway smooth muscle cells: involvement of different promoter elements, transcription factors, and histone h4 acetylation.

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A target for Pl(3) kinase

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Identifiers

10.1152/AJPLUNG.00311.2006

1 reference

Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/17158602

1 reference

Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/17158602

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