Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension. (Q54570348)

1 June 2018

title

Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension. (English)

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1 June 2018

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Gopinath Sutendra

1

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1 June 2018

Peter Dromparis

2

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Sébastien Bonnet

3

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Alois Haromy

4

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Michael S McMurtry

5

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R Chris Bleackley

6

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Evangelos D Michelakis

7

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publication date

2 August 2011

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Journal of Molecular Medicine

published in

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volume

89

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issue

8

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page(s)

771-783

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https://scigraph.springernature.com/pub.10.1007/s00109-011-0762-2

exact match

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cites work

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12 December 2020

Etanercept in children with polyarticular juvenile rheumatoid arthritis. Pediatric Rheumatology Collaborative Study Group

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Sustained membrane depolarization and pulmonary artery smooth muscle cell proliferation.

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12 December 2020

Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity

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12 December 2020

TNF-alpha and IL-1 alpha inhibit both pyruvate dehydrogenase activity and mitochondrial function in cardiomyocytes: evidence for primary impairment of mitochondrial function

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12 December 2020

Effects of TNF-alpha blockade in monocrotaline-induced pulmonary hypertension.

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12 December 2020

In vivo blockade of tumor necrosis factor-alpha in cholesterol-fed rabbits after cardiac transplant inhibits acute coronary artery neointimal formation

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Tumor necrosis factor gene expression in human vascular intimal smooth muscle cells detected by in situ hybridization

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Exuberant endothelial cell growth and elements of inflammation are present in plexiform lesions of pulmonary hypertension

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Overexpression of tumor necrosis factor-alpha produces an increase in lung volumes and pulmonary hypertension

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12 December 2020

10.1007/S00109-011-0762-2

Identifiers

DOI

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1 June 2018

PubMed ID

21809123

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1 June 2018