The apical polarity determinant Crumbs 2 is a novel regulator of ESC-derived neural progenitors. (Q54576271)

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6 February 2020

title

The apical polarity determinant Crumbs 2 is a novel regulator of ESC-derived neural progenitors (English)

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6 February 2020

1

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6 February 2020

author name string

Penny Rashbass

series ordinal

2

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6 February 2020

publication date

1 February 2011

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6 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732478%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

volume

29

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6 February 2020

issue

2

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6 February 2020

page(s)

193-205

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The cell biology of neurogenesis

6 February 2020

cites work

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Neurogenesis and asymmetric cell division

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The Crumbs complex: from epithelial-cell polarity to retinal degeneration

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Polarity complex proteins

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CRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cells

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Direct interaction of two polarity complexes implicated in epithelial tight junction assembly

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Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

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Signal transduction through beta-catenin and specification of cell fate during embryogenesis

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Blocked inhibitory serine-phosphorylation of glycogen synthase kinase-3alpha/beta impairs in vivo neural precursor cell proliferation

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GSK-3 is a master regulator of neural progenitor homeostasis

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Glycogen synthase kinase-3beta induces neuronal cell death via direct phosphorylation of mixed lineage kinase 3.

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Mammalian Par3 regulates progenitor cell asymmetric division via notch signaling in the developing neocortex

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Instructive role of aPKCzeta subcellular localization in the assembly of adherens junctions in neural progenitors

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Par-complex proteins promote proliferative progenitor divisions in the developing mouse cerebral cortex

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Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation.

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The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface

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The apical complex couples cell fate and cell survival to cerebral cortical development

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Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage

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The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy

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Midbody and primary cilium of neural progenitors release extracellular membrane particles enriched in the stem cell marker prominin-1

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Adherens junction domains are split by asymmetric division of embryonic neural stem cells

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Differentiation of rhesus embryonic stem cells to neural progenitors and neurons

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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GSK-3: tricks of the trade for a multi-tasking kinase

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Prominin-1/CD133, a neural and hematopoietic stem cell marker, is expressed in adult human differentiated cells and certain types of kidney cancer.

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Release of extracellular membrane particles carrying the stem cell marker prominin-1 (CD133) from neural progenitors and other epithelial cells

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The ground state of embryonic stem cell self-renewal

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Capturing pluripotency

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Human CRB2 inhibits gamma-secretase cleavage of amyloid precursor protein by binding to the presenilin complex

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Self-refinement of Notch activity through the transmembrane protein Crumbs: modulation of gamma-secretase activity

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Involvement of GSK-3 in regulation of murine embryonic stem cell self-renewal revealed by a series of bisindolylmaleimides

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PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.

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Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin

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Cdc42-mTOR signaling pathway controls Hes5 and Pax6 expression in retinoic acid-dependent neural differentiation

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PAK is regulated by PI3K, PIX, CDC42, and PP2Calpha and mediates focal adhesion turnover in the hyperosmotic stress-induced p38 pathway

21 January 2018

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Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells

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The p21Rac/Cdc42-activated kinases (PAKs).

21 January 2018

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The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer

21 January 2018

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Overexpression of human CRB1 or related isoforms, CRB2 and CRB3, does not regulate the human presenilin complex in culture cells

21 January 2018

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