Deletion of germline promoter PD beta 1 from the TCR beta locus causes hypermethylation that impairs D beta 1 recombination by multiple mechanisms. (Q54584150)

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English	Deletion of germline promoter PD beta 1 from the TCR beta locus causes hypermethylation that impairs D beta 1 recombination by multiple mechanisms.	scientific article

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scholarly article

1 reference

Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/11114382

Deletion of germline promoter PD beta 1 from the TCR beta locus causes hypermethylation that impairs D beta 1 recombination by multiple mechanisms. (English)

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Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/11114382

hypermethylation

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author name string

Whitehurst CE

1

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Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/11114382

Schlissel MS

2

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Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/11114382

Chen J

3

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Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/11114382

language of work or name

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publication date

1 November 2000

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Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/11114382

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Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/11114382

13

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Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/11114382

5

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Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/11114382

703-714

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Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/11114382

Gene activation by histone and factor acetyltransferases

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Global transcription regulators of eukaryotes

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Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility.

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7 January 2021

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Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development

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Developmental regulation of immune system gene rearrangement

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Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus.

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7 January 2021

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Chromatin remodeling directly activates V(D)J recombination

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High sensitivity mapping of methylated cytosines

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Genomic organization of the TcR beta-chain diversity (Dbeta) and joining (Jbeta) segments in the rainbow trout: presence of many repeated sequences.

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Promotion of V(D)J recombinational accessibility by the intronic E kappa element: role of the kappa B motif

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Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibility

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DNA methylation models histone acetylation

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Nuclear matrix attachment regions antagonize methylation-dependent repression of long-range enhancer-promoter interactions

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Recent advances in understanding V(D)J recombination.

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Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase

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Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)

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Antigen receptor gene rearrangement

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Transcription and demethylation of TCR beta gene initiate prior to the gene rearrangement in c-kit+ thymocytes with CD3 expression: evidence of T cell commitment in the thymus.

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Evidence that protein binding specifies sites of DNA demethylation

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Accessibility of nucleosomal DNA to V(D)J cleavage is modulated by RSS positioning and HMG1.

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7 January 2021

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Extension of chromatin accessibility by nuclear matrix attachment regions.

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Relationships between chromatin organization and DNA methylation in determining gene expression

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A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus

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B cell-specific demethylation: a novel role for the intronic kappa chain enhancer sequence

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Modulation of DNA binding protein affinity directly affects target site demethylation

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Chromatin remodeling by the T cell receptor (TCR)-beta gene enhancer during early T cell development: Implications for the control of TCR-beta locus recombination

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An embryonic demethylation mechanism involving binding of transcription factors to replicating DNA

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Stimulation of V(D)J recombination by histone acetylation

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Enhancer control of local accessibility to V(D)J recombinase

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Kappa chain monoallelic demethylation and the establishment of allelic exclusion

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DNA methylation and chromatin modification.

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Dynamics of demethylation and activation of the alpha-actin gene in myoblasts

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Recombination and transcription of the endogenous Ig heavy chain locus is effected by the Ig heavy chain intronic enhancer core region in the absence of the matrix attachment regions

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Accessibility and the developmental regulation of V(D)J recombination

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Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

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Regulation of V(D)J recombination by transcriptional promoters

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Defect in rearrangement of the most 5' TCR-J alpha following targeted deletion of T early alpha (TEA): implications for TCR alpha locus accessibility.

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Control of V(D)J recombinational accessibility of the D beta 1 gene segment at the TCR beta locus by a germline promoter

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Introduced T cell receptor variable region gene segments recombine in pre-B cells: evidence that B and T cells use a common recombinase

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Induction of germline transcription in the TCRgamma locus by Stat5: implications for accessibility control by the IL-7 receptor

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Identifiers

10.1016/S1074-7613(00)00069-8

1 reference

Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/11114382

1 reference

Europe PubMed Central

1 June 2018

http://europepmc.org/abstract/MED/11114382

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