Cystatin cures visceral leishmaniasis by NF-κB-mediated proinflammatory response through co-ordination of TLR/MyD88 signaling with p105-Tpl2-ERK pathway. (Q54624804)

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English	Cystatin cures visceral leishmaniasis by NF-κB-mediated proinflammatory response through co-ordination of TLR/MyD88 signaling with p105-Tpl2-ERK pathway.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21182083

Cystatin cures visceral leishmaniasis by NF-κB-mediated proinflammatory response through co-ordination of TLR/MyD88 signaling with p105-Tpl2-ERK pathway. (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21182083

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toll-like receptor

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visceral leishmaniasis

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inferred from title

author name string

Susanta Kar

1

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Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21182083

Anindita Ukil

2

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21182083

Pijush K Das

3

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Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21182083

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publication date

3 December 2010

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Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21182083

European Journal of Immunology

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Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21182083

41

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Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21182083

1

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Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21182083

116-127

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Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21182083

IRAK4 kinase activity is redundant for interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Tumor progression locus 2 (Map3k8) is critical for host defense against Listeria monocytogenes and IL-1 beta production.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IkappaB kinase-induced proteolysis of NF-kappaB1 p105.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Evasion of innate immunity by parasitic protozoa

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https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Toll-like receptors and leishmaniasis.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Leishmania major activates IL-1 alpha expression in macrophages through a MyD88-dependent pathway

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

MyD88 is essential for clearance of Leishmania major: possible role for lipophosphoglycan and Toll‐like receptor 2 signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Toll-like receptor 4 contributes to efficient control of infection with the protozoan parasite Leishmania major

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of plasmacytoid DCs.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Leishmania lipophosphoglycan (LPG) activates NK cells through toll-like receptor-2.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

RNA interference reveals a role for TLR2 and TLR3 in the recognition of Leishmania donovani promastigotes by interferon-gamma-primed macrophages

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Distinct roles for MyD88 and Toll-like receptor 2 during Leishmania braziliensis infection in mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Successful therapy of lethal murine visceral leishmaniasis with cystatin involves up-regulation of nitric oxide and a favorable T cell response

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Signaling events leading to the curative effect of cystatin on experimental visceral leishmaniasis: involvement of ERK1/2, NF-kappaB and JAK/STAT pathways

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Leishmania-induced IRAK-1 inactivation is mediated by SHP-1 interacting with an evolutionarily conserved KTIM motif

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Immunomodulatory peptide from cystatin, a natural cysteine protease inhibitor, against leishmaniasis as a model macrophage disease

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Host-pathogen interactions: subversion and utilization of the NF-kappa B pathway during infection

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

NF-kappa B1 is required for optimal CD4+ Th1 cell development and resistance to Leishmania major.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

NF-kappa B2 is required for optimal CD40-induced IL-12 production but dispensable for Th1 cell Differentiation.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Lipopolysaccharide-induced tumor necrosis factor-alpha promoter activity is inhibitor of nuclear factor-kappaB kinase-dependent

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Complex NF-kappaB interactions at the distal tumor necrosis factor promoter region in human monocytes.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

IL-1 signaling cascade in liver cells and the involvement of a soluble form of the IL-1 receptor accessory protein

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

MAPK-directed phosphatases preferentially regulate pro- and anti-inflammatory cytokines in experimental visceral leishmaniasis: involvement of distinct protein kinase C isoforms.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

18 Beta-glycyrrhetinic acid triggers curative Th1 response and nitric oxide up-regulation in experimental visceral leishmaniasis associated with the activation of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

21 January 2018

Toll-like receptor signaling pathways

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

7 January 2021

based on heuristic

inferred from DOI database lookup

TLR9 signaling is essential for the innate NK cell response in murine cutaneous leishmaniasis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

7 January 2021

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Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

7 January 2021

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The Rel subunit of NF-kappaB-like transcription factors is a positive and negative regulator of macrophage gene expression: distinct roles for Rel in different macrophage populations

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040533

7 January 2021

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inferred from DOI database lookup

Identifiers

10.1002/EJI.201040533

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21182083

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 June 2018

http://europepmc.org/abstract/MED/21182083

ResearchGate publication ID

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