TGF-beta1 production by CD4+ CD25+ regulatory T cells is not essential for suppression of intestinal inflammation. (Q54641474)

2 June 2018

title

TGF-beta1 production by CD4+ CD25+ regulatory T cells is not essential for suppression of intestinal inflammation. (English)

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2 June 2018

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Alan Sher

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object named as

Alan Sher

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author name string

Marika C Kullberg

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Valerie Hay

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Allen W Cheever

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John J Letterio

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Ethan M Shevach

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Ciriaco A Piccirillo

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language of work or name

English

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publication date

1 October 2005

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2 June 2018

European Journal of Immunology

published in

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2 June 2018

volume

35

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issue

10

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page(s)

2886-2895

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2 June 2018

Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific

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Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: control by CD4+ regulatory T cells and IL-10.

21 January 2018

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Smad3 is essential for TGF-beta 1 to suppress IL-2 production and TCR-induced proliferation, but not IL-2-induced proliferation

21 January 2018

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TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice

21 January 2018

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Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7

21 January 2018

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Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction

21 January 2018

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Cutting Edge: TGF- Signaling Is Required for the In Vivo Expansion and Immunosuppressive Capacity of Regulatory CD4+CD25+ T Cells

21 January 2018

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Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

21 January 2018

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7 January 2021

CD4+ CD25+ suppressor T cells: more questions than answers

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7 January 2021

Naturally-occurring CD4+CD25+ immunoregulatory T cells: central players in the arena of peripheral tolerance

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Control of immune homeostasis by naturally arising regulatory CD4+ T cells

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CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

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Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells

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7 January 2021

Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells

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7 January 2021

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

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Regulation of immune responses by TGF-beta

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Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

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Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

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Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor beta II receptor

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7 January 2021

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

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7 January 2021

CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

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7 January 2021

Control of T-cell activation by CD4+ CD25+ suppressor T cells

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7 January 2021

Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro

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7 January 2021

Human anergic/suppressive CD4(+)CD25(+) T cells: a highly differentiated and apoptosis-prone population

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7 January 2021

CD4+CD25high regulatory cells in human peripheral blood

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7 January 2021

Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood

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7 January 2021

CD28 disruption exacerbates inflammation in Tgf-beta1-/- mice: in vivo suppression by CD4+CD25+ regulatory T cells independent of autocrine TGF-beta1.

1 reference

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7 January 2021

A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

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https://api.crossref.org/works/10.1002%2FEJI.200526106

7 January 2021

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

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7 January 2021

Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo

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7 January 2021

Cornerstone of peripheral tolerance: naturally occurring CD4+CD25+ regulatory T cells

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7 January 2021

Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

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7 January 2021

CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes

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7 January 2021

Transforming growth factor-beta in T-cell biology

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7 January 2021

CD4+CD25- T cells that express latency-associated peptide on the surface suppress CD4+CD45RBhigh-induced colitis by a TGF-beta-dependent mechanism

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200526106

7 January 2021

TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

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https://api.crossref.org/works/10.1002%2FEJI.200526106

7 January 2021

TGF-beta induces Foxp3 + T-regulatory cells from CD4 + CD25 - precursors

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200526106

7 January 2021

IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200526106

7 January 2021

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200526106

7 January 2021

Early-onset multifocal inflammation in the transforming growth factor beta 1-null mouse is lymphocyte mediated

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https://api.crossref.org/works/10.1002%2FEJI.200526106

7 January 2021

Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis

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https://api.crossref.org/works/10.1002%2FEJI.200526106

7 January 2021

Cytokine mRNA expression in intestinal tissue of interleukin-2 deficient mice with bowel inflammation

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7 January 2021

Identifiers

DOI

10.1002/EJI.200526106

1 reference

2 June 2018

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2 June 2018