Protective role of peroxisome proliferator-activated receptor-β/δ in septic shock. (Q54657506)

2 June 2018

title

Protective role of peroxisome proliferator-activated receptor-β/δ in septic shock. (English)

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7

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Roberto Fantozzi

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Helder Mota-Filipe

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Béatrice Desvergne

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Christoph Thiemermann

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object named as

Christoph Thiemermann

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Muhammad Yaqoob Sharrudi

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object named as

Muhammad M Yaqoob

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Marcin Osuchowski

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object named as

Marcin F Osuchowski

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author name string

Amar Kapoor

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Yasunori Shintani

2

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Massimo Collino

3

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Daniel Busch

5

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Nimesh S A Patel

6

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Sara Castiglia

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David Bishop-Bailey

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Ken Suzuki

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Soheyl Bahrami

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Jane A Mitchell

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language of work or name

English

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publication date

6 August 2010

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2 June 2018

American Journal of Respiratory and Critical Care Medicine

published in

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volume

182

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issue

12

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page(s)

1506-1515

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Cardiac dysfunction in sepsis: new theories and clinical implications

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Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy

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The steroid and thyroid hormone receptor superfamily

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Positive regulation of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR)

21 January 2018

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The cyclopentenone prostaglandin 15-deoxydelta(12,14)-prostaglandin J2 attenuates the development of zymosan-induced shock

21 January 2018

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Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces the development of nonseptic shock induced by zymosan in mice

21 January 2018

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PPARbeta/delta protects against experimental colitis through a ligand-independent mechanism.

21 January 2018

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Peroxisome proliferator-activated receptor beta/delta exerts a strong protection from ischemic acute renal failure

21 January 2018

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Modulation of LPS-induced pulmonary neutrophil infiltration and cytokine production by the selective PPARbeta/delta ligand GW0742.

21 January 2018

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The PPARdelta agonist GW0742X reduces atherosclerosis in LDLR(-/-) mice

21 January 2018

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In vivo activation of peroxisome proliferator-activated receptor-delta protects the heart from ischemia/reperfusion injury in Zucker fatty rats

21 January 2018

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Activation of peroxisome proliferator-activated receptor beta/delta inhibits lipopolysaccharide-induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signal-related kinase 1/2.

21 January 2018

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Sepsis and septic shock--a review of laboratory models and a proposal

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PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis

21 January 2018

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Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)--synthesis and biological activity

21 January 2018

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Activation of peroxisome proliferator-activated receptor-beta/delta attenuates myocardial ischemia/reperfusion injury in the rat.

21 January 2018

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Identification and characterization of a selective peroxisome proliferator-activated receptor beta/delta (NR1C2) antagonist.

21 January 2018

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Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

21 January 2018

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Suppression of Pro-inflammatory Adhesion Molecules by PPAR-δ in Human Vascular Endothelial Cells

21 January 2018

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The phosphoinositide 3-kinase pathway

21 January 2018

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Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway.

21 January 2018

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Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth

21 January 2018

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

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Insulin action in cultured human myoblasts: contribution of different signalling pathways to regulation of glycogen synthesis.

21 January 2018

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Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

21 January 2018

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GSK-3beta inhibitors attenuate the organ injury/dysfunction caused by endotoxemia in the rat.

21 January 2018

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The IKK/NF-kappa B pathway

21 January 2018

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Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

21 January 2018

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PPARdelta modulates lipopolysaccharide-induced TNFalpha inflammation signaling in cultured cardiomyocytes

21 January 2018

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PPARalpha and PPARdelta activators inhibit cytokine-induced nuclear translocation of NF-kappaB and expression of VCAM-1 in EAhy926 endothelial cells

21 January 2018

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Peroxisome proliferator-activated receptor beta/delta activation inhibits hypertrophy in neonatal rat cardiomyocytes

21 January 2018

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STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity

21 January 2018

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The PPARdelta agonist GW501516 suppresses interleukin-6-mediated hepatocyte acute phase reaction via STAT3 inhibition

21 January 2018

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Emerging roles of peroxisome proliferator-activated receptor-beta/delta in inflammation

21 January 2018

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10.1164/RCCM.201002-0240OC

21 January 2018

Identifiers

DOI

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2 June 2018

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2 June 2018