Phosphoinositide-3 kinase gamma activity contributes to sepsis and organ damage by altering neutrophil recruitment. (Q54671652)

2 June 2018

title

Phosphoinositide-3 kinase gamma activity contributes to sepsis and organ damage by altering neutrophil recruitment. (English)

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2 June 2018

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7

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Vito Fanelli

8

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Virgínia S. Lemos

12

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Fernando Queiroz Cunha

15

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Emilio Hirsch

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Erica L Martin

Erica L Martin

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Arthur S Slutsky

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Arthur S Slutsky

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2 June 2018

Mauro M Teixeira

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Mauro M Teixeira

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Valeria Puntorieri

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Valeria Puntorieri

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Barbara Assenzio

5

Barbara Assenzio

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2 June 2018

Martino Bosco

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Martino Bosco

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2 June 2018

Luisa Delsedime

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Luisa Delsedime

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2 June 2018

Marco Ranieri

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V Marco Ranieri

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2 June 2018

author name string

Danielle G Souza

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Caio T Fagundes

3

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Flavio A Amaral

4

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Jose F Pinho

11

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Fabricio O Souto

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Jose C Alves-Filho

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Thomas Ruckle

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language of work or name

English

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publication date

27 May 2010

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2 June 2018

American Journal of Respiratory and Critical Care Medicine

published in

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2 June 2018

volume

182

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2 June 2018

issue

6

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2 June 2018

page(s)

762-773

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2 June 2018

Mechanisms of sepsis-induced organ dysfunction

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Down-regulation of CXCR2 on Neutrophils in Severe Sepsis Is Mediated by Inducible Nitric Oxide Synthase–derived Nitric Oxide

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Inhibition of nuclear factor kappaB and phosphatidylinositol 3-kinase/Akt is essential for massive hepatocyte apoptosis induced by tumor necrosis factor alpha in mice

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Lack of phosphoinositide 3-kinase-gamma attenuates ventilator-induced lung injury.

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Phosphoinositide 3-kinase gamma: kinase-dependent and -independent activities in cardiovascular function and disease

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PI3K class IB pathway

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PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects

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Role of phosphatidylinositol 3-kinase-gamma in mediating lung neutrophil sequestration and vascular injury induced by E. coli sepsis.

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Phosphoinositide-3 kinase gamma kinase activity significantly contributes to the pathophysiology of sepsis and multiorgan failure

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Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

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Sepsis: current concepts in intracellular signaling

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The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

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Leading-edge research: PtdIns(3,4,5)P3 and directed migration.

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Importance of Phosphoinositide 3-Kinase γ in the Host Defense against Pneumococcal Infection

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Leukocyte PI3K and PI3K have temporally distinct roles for leukocyte recruitment in vivo

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21 January 2018

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Twice upon a time: PI3K's secret double life exposed

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Protein kinase activity of phosphoinositide 3-kinase regulates beta-adrenergic receptor endocytosis

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10.1164/RCCM.201001-0088OC

21 January 2018

Identifiers

DOI

1 reference

2 June 2018

PubMed ID

20508212

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2 June 2018