Investigation of leucine-rich repeat kinase 2 : enzymological properties and novel assays. (Q54781213)

3 June 2018

title

Investigation of leucine-rich repeat kinase 2 : enzymological properties and novel assays. (English)

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3 June 2018

author name string

Vasanti S Anand

1

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3 June 2018

Laurie J Reichling

2

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3 June 2018

Kerri Lipinski

3

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3 June 2018

Wayne Stochaj

4

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3 June 2018

Weili Duan

5

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3 June 2018

Kerry Kelleher

6

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3 June 2018

Pooja Pungaliya

7

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3 June 2018

Eugene L Brown

8

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3 June 2018

Peter H Reinhart

9

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3 June 2018

Richard Somberg

10

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3 June 2018

Warren D Hirst

11

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3 June 2018

Steven M Riddle

12

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3 June 2018

Steven P Braithwaite

13

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3 June 2018

language of work or name

English

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publication date

1 January 2009

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3 June 2018

published in

FEBS Journal

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3 June 2018

volume

276

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3 June 2018

issue

2

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3 June 2018

page(s)

466-478

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3 June 2018

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

cites work

1 reference

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Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

21 January 2018

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Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

LRRK2 in Parkinson's disease: protein domains and functional insights

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

Kinase activity of mutant LRRK2 mediates neuronal toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

The familial Parkinsonism gene LRRK2 regulates neurite process morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

The Parkinson's disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

Active and inactive protein kinases: structural basis for regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

Autophosphorylation kinetics of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

Expression, purification, and inhibition of human RET tyrosine kinase

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

The protein kinase complement of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

Mutations in LRRK2 as a cause of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

A study of LRRK2 mutations and Parkinson's disease in Brazil

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

Mechanistic insight into the dominant mode of the Parkinson's disease-associated G2019S LRRK2 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06789.X

10.1111/J.1742-4658.2008.06789.X

21 January 2018

Identifiers

DOI

1 reference

3 June 2018

PubMed ID

19076219

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3 June 2018