Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumab. (Q54791338)

3 June 2018

title

Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumab. (English)

1 reference

3 June 2018

author name string

M Pickl

series ordinal

1

1 reference

3 June 2018

C H Ries

series ordinal

2

1 reference

3 June 2018

language of work or name

English

0 references

publication date

3 November 2008

1 reference

3 June 2018

published in

Oncogene

1 reference

3 June 2018

volume

28

1 reference

3 June 2018

issue

3

1 reference

3 June 2018

page(s)

461-468

1 reference

3 June 2018

Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Trastuzumab--mechanism of action and use in clinical practice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Regulation of the interaction of Pak2 with Cdc42 via autophosphorylation of serine 141.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Akt protein kinase inhibits Rac1-GTP binding through phosphorylation at serine 71 of Rac1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Three-dimensional culture models of normal and malignant breast epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Associations of ErbB2, beta1-integrin and lipid rafts on Herceptin (Trastuzumab) resistant and sensitive tumor cell lines.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Lipid rafts and the local density of ErbB proteins influence the biological role of homo- and heteroassociations of ErbB2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Herceptin: mechanisms of action and resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

HER2 amplification ratios by fluorescence in situ hybridization and correlation with immunohistochemistry in a cohort of 6556 breast cancer tissues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Rafts defined: a report on the Keystone Symposium on Lipid Rafts and Cell Function.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Caveolin-1, a putative tumour suppressor gene

31 March 2020

2 references

https://api.crossref.org/works/10.1038%2FONC.2008.394

31 March 2020

https://api.crossref.org/works/10.1038%2FONC.2008.394

inferred from DOI database lookup

7 January 2021

based on heuristic

Human breast cancer cells selected for resistance to trastuzumab in vivo overexpress epidermal growth factor receptor and ErbB ligands and remain dependent on the ErbB receptor network

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Bidirectional signaling between the cytoskeleton and integrins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Use of three-dimensional basement membrane cultures to model oncogene-induced changes in mammary epithelial morphogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

GM3 content modulates the EGF-activated p185c-neu levels, but not those of the constitutively activated oncoprotein p185neu

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Role of gangliosides in the association of ErbB2 with lipid rafts in mammary epithelial HC11 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Effects of ErbB-2 overexpression on mitogenic signalling and cell cycle progression in human breast luminal epithelial cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

HER2 overexpression and cancer targeting

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Modeling tissue morphogenesis and cancer in 3D.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

HER-2 testing in breast cancer using parallel tissue-based methods

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.394

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.394

1 reference

3 June 2018

1 reference

3 June 2018