Aberrant FGFR tyrosine kinase signaling enhances the Warburg effect by reprogramming LDH isoform expression and activity in prostate cancer. (Q54976511)

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English	Aberrant FGFR tyrosine kinase signaling enhances the Warburg effect by reprogramming LDH isoform expression and activity in prostate cancer.	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 June 2018

http://europepmc.org/abstract/MED/29891507

Aberrant FGFR tyrosine kinase signaling enhances the Warburg effect by reprogramming LDH isoform expression and activity in prostate cancer. (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 June 2018

http://europepmc.org/abstract/MED/29891507

author name string

Junchen Liu

1

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Europe PubMed Central

PubMed publication ID

14 June 2018

http://europepmc.org/abstract/MED/29891507

Guo Chen

2

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14 June 2018

http://europepmc.org/abstract/MED/29891507

Zezhen Liu

3

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14 June 2018

http://europepmc.org/abstract/MED/29891507

Shaoyou Liu

4

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14 June 2018

http://europepmc.org/abstract/MED/29891507

Zhiduan Cai

5

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PubMed publication ID

14 June 2018

http://europepmc.org/abstract/MED/29891507

Pan You

6

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14 June 2018

http://europepmc.org/abstract/MED/29891507

Yuepeng Ke

7

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14 June 2018

http://europepmc.org/abstract/MED/29891507

Li Lai

8

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14 June 2018

http://europepmc.org/abstract/MED/29891507

Yun Huang

9

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14 June 2018

http://europepmc.org/abstract/MED/29891507

Hongchang Gao

10

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14 June 2018

http://europepmc.org/abstract/MED/29891507

Liangcai Zhao

11

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14 June 2018

http://europepmc.org/abstract/MED/29891507

Helene Pelicano

12

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PubMed publication ID

14 June 2018

http://europepmc.org/abstract/MED/29891507

Peng Huang

13

1 reference

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PubMed publication ID

14 June 2018

http://europepmc.org/abstract/MED/29891507

Wallace L McKeehan

14

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14 June 2018

http://europepmc.org/abstract/MED/29891507

Chin-Lee Wu

15

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PubMed publication ID

14 June 2018

http://europepmc.org/abstract/MED/29891507

Cong Wang

16

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PubMed publication ID

14 June 2018

http://europepmc.org/abstract/MED/29891507

Weide Zhong

17

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PubMed publication ID

14 June 2018

http://europepmc.org/abstract/MED/29891507

Fen Wang

18

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14 June 2018

http://europepmc.org/abstract/MED/29891507

language of work or name

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publication date

11 June 2018

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Europe PubMed Central

PubMed publication ID

14 June 2018

http://europepmc.org/abstract/MED/29891507

Cancer Research

1 reference

Europe PubMed Central

PubMed publication ID

14 June 2018

http://europepmc.org/abstract/MED/29891507

FGF-dependent metabolic control of vascular development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

LDHB may be a significant predictor of poor prognosis in osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Exercise Inducible Lactate Dehydrogenase B Regulates Mitochondrial Function in Skeletal Muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Lactate Dehydrogenase B Controls Lysosome Activity and Autophagy in Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Metabolic Alterations in Renal and Prostate Cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Low Expression of LDHB Correlates With Unfavorable Survival in Hepatocellular Carcinoma: Strobe-Compliant Article

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Overexpression of FGF9 in prostate epithelial cells augments reactive stroma formation and promotes prostate cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Inhibition of LDHA suppresses tumor progression in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

A glycolytic phenotype is associated with prostate cancer progression and aggressiveness: a role for monocarboxylate transporters as metabolic targets for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Suppressed expression of LDHB promotes pancreatic cancer progression via inducing glycolytic phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Type 1 fibroblast growth factor receptor in cranial neural crest cell-derived mesenchyme is required for palatogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Lactate dehydrogenase B: a metabolic marker of response to neoadjuvant chemotherapy in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

FGFR1 is essential for prostate cancer progression and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Metabolic reprogramming and validation of hyperpolarized 13C lactate as a prostate cancer biomarker using a human prostate tissue slice culture bioreactor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Lysine-5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Lactate dehydrogenase B is required for the growth of KRAS-dependent lung adenocarcinomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

An integrated genomic screen identifies LDHB as an essential gene for triple-negative breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD(+) redox homeostasis in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Decreased lactate dehydrogenase B expression enhances claudin 1-mediated hepatoma cell invasiveness via mitochondrial defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Lactate dehydrogenase B is critical for hyperactive mTOR-mediated tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Integrative genomic profiling of human prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Role of epithelial cell fibroblast growth factor receptor substrate 2alpha in prostate development, regeneration and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

FGFR1 and WT1 are markers of human prostate cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Branched-chain amino acids improve glucose metabolism in rats with liver cirrhosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

The fibroblast growth factor receptor-4 Arg388 allele is associated with prostate cancer initiation and progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Promoter hypermethylation in cancer silences LDHB, eliminating lactate dehydrogenase isoenzymes 1-4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Role of fibroblast growth factor receptor signaling in prostate cancer cell survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Carcinoma of the prostate. II. Serum activity of acid phosphatase, prostatic acid phosphatase, LDH and its isoenzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6095720

7 September 2018

Carcinoma of the prostate. I. Histochemical examination as an aid in evaluating prostate carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29891507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer-Associated Lactate Dehydrogenase is a Tyrosylphosphorylated Form of Human LDH-A, Skeletal Muscle Isoenzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/29891507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LDH isoenzymes in benign and malignant prostate tissue. The LDH V-I ratio as an index of malignancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29891507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rabbit muscle lactate dehydrogenase 5; a regulatory enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/29891507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/29891507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in expression of basic fibroblast growth factor (FGF) 2 and its receptor FGFR-1 in human prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29891507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of tumor cell-derived lactic acid on human T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29891507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lactate dehydrogenase is a prognostic indicator for prostate cancer patients with bone metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29891507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FGF signaling in prostate tumorigenesis--new insights into epithelial-stromal interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/29891507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of CD147 is associated with prostate cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/29891507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of lactate dehydrogenase B according to histologic type of non-small-cell lung cancer and its association with serum lactate dehydrogenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29891507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-17-3226

1 reference

Europe PubMed Central

PubMed publication ID

14 June 2018

http://europepmc.org/abstract/MED/29891507

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 June 2018

http://europepmc.org/abstract/MED/29891507

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