USPC-ARK-2 (Q54991963)

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cell line

USPC ARK-2
USPC-ARK2
USC ARK-2
ARK-2
ARK2

Language	Label	Description	Also known as
English	USPC-ARK-2	cell line	USPC ARK-2 USPC-ARK2 USC ARK-2 ARK-2 ARK2

Statements

1 reference

Cellosaurus release 44

31 January 2023

cancer cell line

1 reference

Cellosaurus release 44

31 January 2023

described by source

In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinoma

1 reference

Cellosaurus release 44

31 January 2023

Uterine serous papillary carcinomas overexpress human trophoblast-cell-surface marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized anti-Trop-2 monoclonal antibody

1 reference

Cellosaurus release 44

31 January 2023

Oncogenic PIK3CA gene mutations and HER2/neu gene amplifications determine the sensitivity of uterine serous carcinoma cell lines to GDC-0980, a selective inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2).

1 reference

Cellosaurus release 44

31 January 2023

PIK3CA oncogenic mutations represent a major mechanism of resistance to trastuzumab in HER2/neu overexpressing uterine serous carcinomas

1 reference

Cellosaurus release 44

31 January 2023

Afatinib demonstrates remarkable activity against HER2-amplified uterine serous endometrial cancer in vitro and in vivo.

1 reference

Cellosaurus release 44

31 January 2023

PIK3CA oncogenic mutations represent a major mechanism of resistance to trastuzumab in HER2/neu overexpressing uterine serous carcinomas

1 reference

Cellosaurus release 44

31 January 2023

Polymerase ε (POLE) ultra-mutation in uterine tumors correlates with T lymphocyte infiltration and increased resistance to platinum-based chemotherapy in vitro.

1 reference

Cellosaurus release 44

31 January 2023

established from medical condition

uterine corpus serous adenocarcinoma

1 reference

Cellosaurus release 26

14 June 2018

derived from organism type

1 reference

Cellosaurus release 44

31 January 2023

Identifiers

1 reference

Cellosaurus release 44

31 January 2023

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