Gastric inhibitory polypeptide receptor (Q5526785)

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mammalian protein found in Homo sapiens

• glucose-dependent insulinotropic polypeptide receptor
• gastric inhibitory polypeptide receptor
• GIPR
• GIP-R

edit

Language	Label	Description	Also known as
English	Gastric inhibitory polypeptide receptor	mammalian protein found in Homo sapiens	glucose-dependent insulinotropic polypeptide receptor gastric inhibitory polypeptide receptor GIPR GIP-R

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P48546

part of

GPCR family 2, extracellular hormone receptor domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P48546

GPCR, family 2, gastric inhibitory polypeptide receptor

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P48546

G protein-coupled receptor

1 reference

Transporter Classification Database ID

9.A.14.4.5

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

GPCR, family 2, extracellular hormone receptor domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

GPCR, family 2-like

1 reference

based on heuristic

inferred from protein domain or family

GPCR, family 2, secretin-like, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P48546

encoded by

GIPR

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P48546

molecular function

G protein-coupled receptor activity

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P48546

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

signal transducer activity

determination method

IEA

1 reference

retrieved

24 April 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P48546

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48546&geneProductId=UniProtKB:P48546

determination method

IEA

gastric inhibitory peptide receptor activity

determination method

IEA

2 references

retrieved

24 April 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48546&geneProductId=UniProtKB:P48546

determination method

IEA

retrieved

24 April 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48546&geneProductId=UniProtKB:P48546

determination method

IEA

transmembrane signaling receptor activity

determination method

TAS

IEA

2 references

retrieved

8 April 2019

stated in

Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

protein binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IPI

peptide hormone binding

determination method

IEA

1 reference

retrieved

24 April 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48546&geneProductId=UniProtKB:P48546

determination method

IEA

G protein-coupled peptide receptor activity

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IBA

gastric inhibitory peptide receptor activity

determination method

IBA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IBA

peptide hormone binding

determination method

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IBA

cell component

integral component of membrane

determination method

IEA

TAS

3 references

retrieved

8 April 2019

stated in

Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P48546

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

membrane

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P48546

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

plasma membrane

determination method

TAS

IEA

4 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

TAS

retrieved

8 April 2019

stated in

Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P48546

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

biological process

response to fatty acid

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

response to nutrient

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

TAS

regulation of insulin secretion

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

TAS

positive regulation of cytosolic calcium ion concentration

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

response to glucose

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

generation of precursor metabolites and energy

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

TAS

activation of adenylate cyclase activity

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Molecular cloning, functional expression, and signal transduction of the GIP‐receptor cloned from a human insulinoma

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

TAS

response to calcium ion

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

cell surface receptor signaling pathway

determination method

IEA

TAS

2 references

retrieved

8 April 2019

stated in

Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

gastric inhibitory peptide signaling pathway

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

response to axon injury

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

desensitization of G protein-coupled receptor signaling pathway

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

endocrine pancreas development

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

signal transduction

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P48546

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

positive regulation of insulin secretion

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

G protein-coupled receptor signaling pathway

determination method

IEA

TAS

3 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P48546

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

positive regulation of cAMP-mediated signaling

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48546

determination method

IEA

physically interacts with

tirzepatide

object of statement has role

agonist

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL4297839

Gene Atlas image

PBB GE GIPR 208105 at fs.png
732 × 530; 12 KB

0 references

exact match

http://purl.uniprot.org/uniprot/P48546

1 reference

stated in

Identifiers.org

has part(s)

GPCR, family 2, extracellular hormone receptor domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P48546

GPCR, family 2, secretin-like, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P48546

GPCR, family 2-like

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P48546

Identifiers

RefSeq protein ID

NP_000155

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2696

NP_001295347

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2696

XP_011525011

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2696

XP_011525012

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2696

XP_011525013

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2696

XP_011525015

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2696

XP_011525016

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2696

XP_011525017

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2696

XP_011525018

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2696

XP_016882073

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2696

XP_016882074

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2696

XP_016882075

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2696

XP_016882076

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2696

UniProt protein ID

P48546

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P48546

Ensembl protein ID

ENSP00000467494

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000467494

ENSP00000263281

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000263281

ENSP00000305321

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000305321

ENSP00000465385

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000465385

ENSP00000467342

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000467342

ENSP00000498426

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000498426

PDB structure ID

4HJ0

1 reference

stated in

UniProt

UniProt protein ID

P48546

retrieved

9 August 2016

language of work or name

English

2QKH

1 reference

stated in

UniProt

UniProt protein ID

P48546

retrieved

9 August 2016

language of work or name

English

Transporter Classification Database ID

9.A.14.4.5

2 references

stated in

Transporter Classification database

retrieved

13 March 2020

stated in

Transporter Classification database

retrieved

29 April 2020

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q5526785&oldid=2098114760"