Targetable BET proteins- and E2F1-dependent transcriptional program maintains the malignancy of glioblastoma. (Q55457087)

http://europepmc.org/abstract/MED/29764999

11 July 2018

title

Targetable BET proteins- and E2F1-dependent transcriptional program maintains the malignancy of glioblastoma. (English)

1 reference

http://europepmc.org/abstract/MED/29764999

11 July 2018

author

Liang Xu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Edwin Sandanaraj

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Dennis Kappei

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Anand Mayakonda

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Moli Huang

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Huy Q Dinh

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Ling-Wen Ding

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Carol Tang

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Ye Chen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Lynnette Koh

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Yuk Kien Chong

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Dennis L Buckley

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

See Wee Lim

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Ruby Yu-Tong Lin

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Xin-Yu Ke

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Jianxiang Chen

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Wendi Sun

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Ling-Zhi Wang

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Boon Cher Goh

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Georg E Winter

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Beng Ti Ang

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Benjamin P Berman

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

James E Bradner

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

H Phillip Koeffler

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

0 references

publication date

15 May 2018

1 reference

http://europepmc.org/abstract/MED/29764999

11 July 2018

published in

Proceedings of the National Academy of Sciences of the United States of America

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

E5086-E5095

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment.

13 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Resistance to BET Bromodomain Inhibitors Is Mediated by Kinome Reprogramming in Ovarian Cancer

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

BET inhibitor resistance emerges from leukaemia stem cells

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

DRUG DEVELOPMENT. Phthalimide conjugation as a strategy for in vivo target protein degradation

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

BET bromodomain proteins are required for glioblastoma cell proliferation.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Glioblastoma: from molecular pathology to targeted treatment

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

AURKA governs self-renewal capacity in glioma-initiating cells via stabilization/activation of β-catenin/Wnt signaling

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Inhibition of BET bromodomain targets genetically diverse glioblastoma

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

BET domain co-regulators in obesity, inflammation and cancer

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Polo-like kinase 1 inhibition kills glioblastoma multiforme brain tumor cells in part through loss of SOX2 and delays tumor progression in mice.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Aurora kinase B/C inhibition impairs malignant glioma growth in vivo.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Selective inhibition of BET bromodomains

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

The transcriptional network for mesenchymal transformation of brain tumours.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Rembrandt: helping personalized medicine become a reality through integrative translational research

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Cryopreservation of neurospheres derived from human glioblastoma multiforme

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

ICOVIR-5 shows E2F1 addiction and potent antiglioma effect in vivo.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Brd2 is a TBP-associated protein and recruits TBP into E2F-1 transcriptional complex in response to serum stimulation

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5984485

Isolation of cancer stem cells from adult glioblastoma multiforme

29 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29764999

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1712363115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

release_tfrp73gbojampbwvrveimktexi

13 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tfrp73gbojampbwvrveimktexi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29764999%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference