Metabolism unhinged: IDH mutations in cancer. (Q55463331)

12 July 2018

title

Metabolism unhinged: IDH mutations in cancer. (English)

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12 July 2018

author

John R. Prensner

series ordinal

1

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12 July 2018

author name string

Arul M Chinnaiyan

series ordinal

2

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12 July 2018

language of work or name

English

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publication date

1 March 2011

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12 July 2018

published in

Nature Medicine

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12 July 2018

volume

17

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12 July 2018

issue

3

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12 July 2018

page(s)

291-293

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12 July 2018

Cancer-associated IDH mutations: biomarker and therapeutic opportunities

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNM0311-291

An integrated genomic analysis of human glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0311-291

IDH1 and IDH2 mutations in gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0311-291

Recurring mutations found by sequencing an acute myeloid leukemia genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0311-291

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0311-291

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0311-291

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0311-291

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0311-291

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0311-291

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0311-291

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0311-291

IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0311-291

21 January 2018

Identifiers

DOI

10.1038/NM0311-291

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12 July 2018

Dimensions Publication ID

1041553300

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Fatcat ID

release_5ll7f43lind3dn3j45v5o4inge

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5ll7f43lind3dn3j45v5o4inge

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

12 July 2018