Preclinical comparison of proteasome and ubiquitin E1 enzyme inhibitors in cutaneous squamous cell carcinoma: the identification of mechanisms of differential sensitivity. (Q55476988)

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scientific article published on 17 April 2018

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English	Preclinical comparison of proteasome and ubiquitin E1 enzyme inhibitors in cutaneous squamous cell carcinoma: the identification of mechanisms of differential sensitivity.	scientific article published on 17 April 2018

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26 March 2020

Preclinical comparison of proteasome and ubiquitin E1 enzyme inhibitors in cutaneous squamous cell carcinoma: the identification of mechanisms of differential sensitivity (English)

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26 March 2020

Charlotte Proby

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26 March 2020

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Angela McHugh

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26 March 2020

Kenneth Fernandes

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26 March 2020

Andrew P South

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26 March 2020

Jemima E Mellerio

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26 March 2020

Julio C Salas-Alanís

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26 March 2020

Irene M Leigh

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26 March 2020

Mark K Saville

8

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26 March 2020

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17 April 2018

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26 March 2020

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26 March 2020

9

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26 March 2020

29

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26 March 2020

20265-20281

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26 March 2020

Varied Role of Ubiquitylation in Generating MHC Class I Peptide Ligands.

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The integrated stress response and proteotoxicity in cancer therapy

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Orthogonal ubiquitin transfer identifies ubiquitination substrates under differential control by the two ubiquitin activating enzymes

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Dynamic transcription of ubiquitin genes under basal and stressful conditions and new insights into the multiple UBC transcript variants.

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Phase 1 study of ixazomib, an investigational proteasome inhibitor, in advanced non-hematologic malignancies

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MYC and EGR1 synergize to trigger tumor cell death by controlling NOXA and BIM transcription upon treatment with the proteasome inhibitor bortezomib

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Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system.

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Structural and functional insights to ubiquitin-like protein conjugation.

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Perilous journey: a tour of the ubiquitin-proteasome system

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Interventions for non-metastatic squamous cell carcinoma of the skin: systematic review and pooled analysis of observational studies

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15 July 2018

BAK and NOXA are critical determinants of mitochondrial apoptosis induced by bortezomib in mesothelioma

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EGFR and MYC gene copy number aberrations are more common in squamous cell carcinoma than keratoacanthoma: a FISH study

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Molecular basis of differential sensitivity of myeloma cells to clinically relevant bolus treatment with bortezomib

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Cutaneous squamous cell carcinoma: estimated incidence of disease, nodal metastasis, and deaths from disease in the United States, 2012.

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New proteasome inhibitors in myeloma

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Chemotherapy of squamous cell carcinoma of the skin

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Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins.

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Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma

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15 July 2018

Isolation and culture of squamous cell carcinoma lines

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15 July 2018

USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis.

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Genome-wide siRNA screen for modulators of cell death induced by proteasome inhibitor bortezomib

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Treatment of skin cancers in epidermolysis bullosa

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Evaluation of the proteasome inhibitor MLN9708 in preclinical models of human cancer

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Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways

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Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53

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12 December 2020

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12 December 2020

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12 December 2020

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inferred from PubMed ID database lookup

MYC gene numerical aberrations in actinic keratosis and cutaneous squamous cell carcinoma

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12 December 2020

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inferred from PubMed ID database lookup

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10.18632/ONCOTARGET.24750

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26 March 2020

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26 March 2020

PubMed publication ID

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26 March 2020

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