Mesenchymal Progenitors Aging Highlights a miR-196 Switch Targeting HOXB7 as Master Regulator of Proliferation and Osteogenesis (Q56097549)

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23 February 2020

title

Mesenchymal progenitors aging highlights a miR-196 switch targeting HOXB7 as master regulator of proliferation and osteogenesis (English)

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23 February 2020

1

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23 February 2020

Giulia Grisendi

4

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23 February 2020

Maria Serena Piccinno

6

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23 February 2020

Manuela Ferracin

7

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23 February 2020

Massimo Negrini

8

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23 February 2020

Pierfranco Conte

12

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23 February 2020

Massimo Dominici

14

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23 February 2020

author name string

Carlotta Spano

2

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23 February 2020

Alba Murgia

3

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23 February 2020

Elena Veronesi

5

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23 February 2020

Francesca Giacobbi

9

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23 February 2020

Franco Bambi

10

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23 February 2020

Edwin Mark Horwitz

11

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23 February 2020

Paolo Paolucci

13

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publication date

1 March 2015

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23 February 2020

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23 February 2020

volume

33

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23 February 2020

issue

3

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23 February 2020

page(s)

939-950

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Mesenchymal stem cells: building blocks for molecular medicine in the 21st century

23 February 2020

cites work

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Donor cell-derived osteopoiesis originates from a self-renewing stem cell with a limited regenerative contribution after transplantation

21 January 2018

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Mesenchymal stem cells are injured by complement after their contact with serum

21 January 2018

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Concise review: hematopoietic stem cell aging, life span, and transplantation

21 January 2018

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Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells

21 January 2018

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Aging of mesenchymal stem cells

21 January 2018

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Replicative senescence of mesenchymal stem cells: a continuous and organized process

21 January 2018

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Aging alters tissue resident mesenchymal stem cell properties.

21 January 2018

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DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells

21 January 2018

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MicroRNA profiling reveals age-dependent differential expression of nuclear factor κB and mitogen-activated protein kinase in adipose and bone marrow-derived human mesenchymal stem cells

21 January 2018

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A mesenchymal stromal cell gene signature for donor age

21 January 2018

1 reference

Phenotype, donor age and gender affect function of human bone marrow-derived mesenchymal stromal cells

21 January 2018

1 reference

Aging and replicative senescence have related effects on human stem and progenitor cells

21 January 2018

1 reference

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

21 January 2018

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miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging

21 January 2018

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microRNA expression patterns reveal differential expression of target genes with age.

21 January 2018

1 reference

The expression of microRNA and microRNA clusters in the aging heart

21 January 2018

1 reference

Reactivation of Hox gene expression during bone regeneration

21 January 2018

1 reference

Enforced expression of HOXB7 promotes hematopoietic stem cell proliferation and myeloid-restricted progenitor differentiation

21 January 2018

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Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation.

21 January 2018

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Transportation conditions for prompt use of ex vivo expanded and freshly harvested clinical-grade bone marrow mesenchymal stromal/stem cells for bone regeneration

21 January 2018

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HOXB7 mRNA is overexpressed in pancreatic ductal adenocarcinomas and its knockdown induces cell cycle arrest and apoptosis

21 January 2018

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MicroRNA profiling for the identification of cancers with unknown primary tissue-of-origin

21 January 2018

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Analyzing real-time PCR data by the comparative C(T) method

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High-efficiency transduction and long-term gene expression with a murine stem cell retroviral vector encoding the green fluorescent protein in human marrow stromal cells

21 January 2018

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Clinical-grade production of human mesenchymal stromal cells: occurrence of aneuploidy without transformation

21 January 2018

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Age-dependent neuroectodermal differentiation capacity of human mesenchymal stromal cells: limitations for autologous cell replacement strategies.

21 January 2018

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MicroRNA-196: critical roles and clinical applications in development and cancer

21 January 2018

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miR-196a regulates proliferation and osteogenic differentiation in mesenchymal stem cells derived from human adipose tissue

21 January 2018

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Hox genes: choreographers in neural development, architects of circuit organization

21 January 2018

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HOXB7 constitutively activates basic fibroblast growth factor in melanomas

21 January 2018

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The role of bFGF on the ability of MSC to activate endogenous regenerative mechanisms in an ectopic bone formation model.

21 January 2018

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Analysis of Hoxa7/Hoxb7 mutants suggests periodicity in the generation of the different sets of vertebrae

21 January 2018

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Targeted mutations in hoxa-9 and hoxb-9 reveal synergistic interactions

21 January 2018

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Functional impairment of bone formation in the pathogenesis of osteoporosis: the bone marrow regenerative competence

21 January 2018

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Aging of marrow stromal (skeletal) stem cells and their contribution to age-related bone loss

21 January 2018

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Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia.

21 January 2018

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Telomerase promoter reprogramming and interaction with general transcription factors in the human mesenchymal stem cell.

21 January 2018

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miR-10a restores human mesenchymal stem cell differentiation by repressing KLF4.

21 January 2018

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Murine mesenchymal and embryonic stem cells express a similar Hox gene profile

21 January 2018

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Hox genes in hematopoiesis and leukemogenesis.

21 January 2018

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Hox transcription factor regulation of adult bone-marrow-derived cell behaviour during tissue repair and regeneration

21 January 2018

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HOXB4-induced expansion of adult hematopoietic stem cells ex vivo.

21 January 2018

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HOXB4's road map to stem cell expansion

21 January 2018

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HOXB7 as a prognostic factor and mediator of colorectal cancer progression

21 January 2018

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HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma

21 January 2018

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MicroRNA miR-196a is a central regulator of HOX-B7 and BMP4 expression in malignant melanoma

21 January 2018

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MicroRNA-196b regulates the homeobox B7-vascular endothelial growth factor axis in cervical cancer.

21 January 2018

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Roles of FGF signaling in stem cell self-renewal, senescence and aging

21 January 2018

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Microarray expression profiling identifies genes with altered expression in Adolescent Idiopathic Scoliosis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/STEM.1897

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23 February 2020

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