Isothermal titration calorimetry: application to structure-based drug design (Q56452981)

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7 January 2021

Counting the calories to stay in the groove.

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7 January 2021

Sensing the heat: the application of isothermal titration calorimetry to thermodynamic studies of biomolecular interactions

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7 January 2021

Isothermal titration calorimetry and differential scanning calorimetry as complementary tools to investigate the energetics of biomolecular recognition

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7 January 2021

Rapid measurement of binding constants and heats of binding using a new titration calorimeter

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7 January 2021

Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study

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7 January 2021

Searching for specificity in SH domains

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7 January 2021

Molecular Anchoring of Duplex and Triplex DNA by Disubstituted Anthracene-9,10-diones: Calorimetric, UV Melting, and Competition Dialysis Studies

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7 January 2021

Coupling of local folding to site-specific binding of proteins to DNA

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7 January 2021

Heat capacity changes and hydrophobic interactions in the binding of FK506 and rapamycin to the FK506 binding protein

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7 January 2021

Multivalent Ligand-Receptor Binding Interactions in the Fibroblast Growth Factor System Produce a Cooperative Growth Factor and Heparin Mechanism for Receptor Dimerization

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7 January 2021

Energetics of drug-DNA interactions

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7 January 2021

Drug-DNA recognition: energetics and implications for design

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7 January 2021

Allosteric properties of inosine monophosphate dehydrogenase revealed through the thermodynamics of binding of inosine 5'-monophosphate and mycophenolic acid. Temperature dependent heat capacity of binding as a signature of ligand-coupled conformati

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7 January 2021

Water-mediated protein-DNA interactions: the relationship of thermodynamics to structural detail

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7 January 2021

Large heat capacity change in a protein-monovalent cation interaction

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7 January 2021

Specific binding of hoechst 33258 to the d(CGCAAATTTGCG)2 duplex: calorimetric and spectroscopic studies

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7 January 2021

Role of the hydrophobic effect in stability of site-specific protein-DNA complexes

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7 January 2021

Thermodynamic mapping of the inhibitor site of the aspartic protease endothiapepsin

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7 January 2021

The role of water in sequence-independent ligand binding by an oligopeptide transporter protein

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7 January 2021

Just add water! The effect of water on the specificity of protein-ligand binding sites and its potential application to drug design

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7 January 2021

The entropic penalty of ordered water accounts for weaker binding of the antibiotic novobiocin to a resistant mutant of DNA gyrase: a thermodynamic and crystallographic study

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7 January 2021