Role of BCL2L10 methylation and TET2 mutations in higher risk myelodysplastic syndromes treated with 5-Azacytidine (Q56773016)

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7 February 2020

title

Role of BCL2L10 methylation and TET2 mutations in higher risk myelodysplastic syndromes treated with 5-azacytidine (English)

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1

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Emiliano Fabiani

2

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Emanuele Angelucci

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Pellegrino Musto

10

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Marianna Criscuolo

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Luana Fianchi

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Marco Vignetti

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Valeria Santini

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Stefan Hohaus

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Giuseppe Leone

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author name string

A Piciocchi

3

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C Matteucci

4

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L Brandimarte

5

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C Finelli

6

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E Pogliani

7

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G Fioritoni

9

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M Greco

11

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C Mecucci

17

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publication date

15 July 2011

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volume

25

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issue

12

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page(s)

1910-1913

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Mutation in TET2 in myeloid cancers

7 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.170

Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.170

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

21 January 2018

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Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

21 January 2018

1 reference

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Valproic acid at therapeutic plasma levels may increase 5-azacytidine efficacy in higher risk myelodysplastic syndromes.

21 January 2018

1 reference

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Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

21 January 2018

1 reference

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Analysis of genome-wide methylation and gene expression induced by 5-aza-2'-deoxycytidine identifies BCL2L10 as a frequent methylation target in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.170

TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.170

Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.170

Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS.

21 January 2018

1 reference

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Myc sensitizes p53-deficient cancer cells to the DNA-damaging effects of the DNA methyltransferase inhibitor decitabine

21 January 2018

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Loss of BCL2L10 protein expression as prognostic predictor for poor clinical outcome in gastric carcinoma

21 January 2018

1 reference

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Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/LEU.2011.170

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7 February 2020

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