From genotype to phenotype: can systems biology be used to predict Staphylococcus aureus virulence? (Q56780177)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

From genotype to phenotype: can systems biology be used to predict Staphylococcus aureus virulence? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

main subject

Staphylococcus aureus

1 reference

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Justine Rudkin

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Jean van den Elsen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Maisem Laabei

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Mario Recker

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Ruth C. Massey

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

5

Ambrose Cheung

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Sharon J Peacock

6

0 references

author name string

Edward J Feil

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

David A Lucks

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

language of work or name

English

0 references

publication date

1 November 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Microbiology

15 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

page(s)

791-797

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

Whole-genome random sequencing and assembly of Haemophilus influenzae Rd

15 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

A systems biology approach to infectious disease research: innovating the pathogen-host research paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Genetic characterization indicates that a specific subpopulation of Pseudomonas aeruginosa is associated with keratitis infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Methicillin-susceptible Staphylococcus aureus endocarditis isolates are associated with clonal complex 30 genotype and a distinct repertoire of enterotoxins and adhesins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Association between phylogeny, virulence potential and serovars of Salmonella enterica

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Strain diversity, epistasis and the evolution of drug resistance in Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Compensatory adaptation to the deleterious effect of antibiotic resistance in Salmonella typhimurium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Positive epistasis drives the acquisition of multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

The cost of multiple drug resistance in Pseudomonas aeruginosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Modeling and simulation of genetic regulatory systems: a literature review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

The Inferelator: an algorithm for learning parsimonious regulatory networks from systems-biology data sets de novo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Gene regulatory network inference: data integration in dynamic models-a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Noise and robustness in prokaryotic regulatory networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Mathematical modeling of gene expression: a guide for the perplexed biologist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Reconstruction of microbial transcriptional regulatory networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Mathematical modelling of the regulation of spa (protein A) transcription in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Integration of 'omics' data: does it lead to new insights into host-microbe interactions?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Validation of gene regulatory networks: scientific and inferential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Systems analysis of multiple regulator perturbations allows discovery of virulence factors in Salmonella

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Staphylococcus aureus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Pathogenesis of methicillin-resistant Staphylococcus aureus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Basis of Virulence in Community-Associated Methicillin-ResistantStaphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Community-associated meticillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Surface adhesins of Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Immune evasion by staphylococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Staphylococcal innate immune evasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Regulation of virulence determinants in vitro and in vivo in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

The Staphylococcus aureus RNome and its commitment to virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Offsetting virulence and antibiotic resistance costs by MRSA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Methicillin resistance reduces the virulence of healthcare-associated methicillin-resistant Staphylococcus aureus by interfering with the agr quorum sensing system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

sigmaB modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

A point mutation in the sensor histidine kinase SaeS of Staphylococcus aureus strain Newman alters the response to biocide exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Transcriptional profiling of a Staphylococcus aureus clinical isolate and its isogenic agr and sarA mutants reveals global differences in comparison to the laboratory strain RN6390.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Staphylococcus aureus host cell invasion and virulence in sepsis is facilitated by the multiple repeats within FnBPA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Potential associations between severity of infection and the presence of virulence-associated genes in clinical strains of Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Risk factors for hematogenous complications of intravascular catheter-associated Staphylococcus aureus bacteremia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Fibrinogen and fibronectin binding cooperate for valve infection and invasion in Staphylococcus aureus experimental endocarditis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Global analysis of community-associated methicillin-resistant Staphylococcus aureus exoproteins reveals molecules produced in vitro and during infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Inferring genetic networks and identifying compound mode of action via expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Developments in statistical analysis in quantitative genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Insights on Evolution of Virulence and Resistance from the Complete Genome Analysis of an Early Methicillin-Resistant Staphylococcus aureus Strain and a Biofilm-Producing Methicillin-Resistant Staphylococcus epidermidis Strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Genome sequence of a recently emerged, highly transmissible, multi-antibiotic- and antiseptic-resistant variant of methicillin-resistant Staphylococcus aureus, sequence type 239 (TW).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Genome and virulence determinants of high virulence community-acquired MRSA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Whole genome sequencing of meticillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Network component analysis: reconstruction of regulatory signals in biological systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Using network component analysis to dissect regulatory networks mediated by transcription factors in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Rapid whole-genome sequencing for investigation of a neonatal MRSA outbreak

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Molecular tracing of the emergence, adaptation, and transmission of hospital-associated methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Understanding gene sequence variation in the context of transcription regulation in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Interactome networks and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Mobile genetic element-encoded cytolysin connects virulence to methicillin resistance in MRSA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Systems biology of persistent infection: tuberculosis as a case study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Integrating 'omic' information: a bridge between genomics and systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Systems biology: a brief overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Bacterial competition for human nasal cavity colonization: role of Staphylococcal agr alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Bacterial interference caused by autoinducing peptide variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Agr interference between clinical Staphylococcus aureus strains in an insect model of virulence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

The human nasal microbiota and Staphylococcus aureus carriage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Transcription profiling-based identification of Staphylococcus aureus genes regulated by the agr and/or sarA loci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Interconnections between Sigma B, agr, and proteolytic activity in Staphylococcus aureus biofilm maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Microarray-based analysis of the Staphylococcus aureus sigmaB regulon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Regulation of Rot expression in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Repression of hla by rot is dependent on sae in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Global regulation of Staphylococcus aureus genes by Rot

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

sarU, a sarA homolog, is repressed by SarT and regulates virulence genes in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

SarT influences sarS expression in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Crystal Structure of the SarS Protein from Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

SarS, a SarA homolog repressible by agr, is an activator of protein A synthesis in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

The staphylococcus-specific gene rsr represses agr and virulence in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

The virulence regulator Sae of Staphylococcus aureus: promoter activities and response to phagocytosis-related signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

SaeR binds a consensus sequence within virulence gene promoters to advance USA300 pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

The two-component system ArlS-ArlR is a regulator of virulence gene expression in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Identification of a novel two-component regulatory system that acts in global regulation of virulence factors of Staphylococcus aureus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Staphylococcus aureus CodY negatively regulates virulence gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Analysis of genetic elements controlling Staphylococcus aureus lrgAB expression: potential role of DNA topology in SarA regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Regulation and characterization of rot transcription in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

sarZ, a sarA family gene, is transcriptionally activated by MgrA and is involved in the regulation of genes encoding exoproteins in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

SarZ promotes the expression of virulence factors and represses biofilm formation by modulating SarA and agr in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Expression of SarX, a negative regulator of agr and exoprotein synthesis, is activated by MgrA in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Identification of sarV (SA2062), a new transcriptional regulator, is repressed by SarA and MgrA (SA0641) and involved in the regulation of autolysis in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Characterization of sarR, a modulator of sar expression in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

The SarA protein family of Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Role of mgrA and sarA in methicillin-resistant Staphylococcus aureus autolysis and resistance to cell wall-active antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Direct targets of CodY in Staphylococcus aureus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

Staphylococcus aureus ClpC divergently regulates capsule via sae and codY in strain newman but activates capsule via codY in strain UAMS-1 and in strain Newman with repaired saeS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

How to infer gene networks from expression profiles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2880

How to infer gene networks from expression profiles

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23070558

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRMICRO2880

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23070558%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference