Influence of atopic heredity on IL-4-, IL-12- and IFN-gamma-producing cells in in vitro activated cord blood mononuclear cells (Q56827948)

6

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author name string

A Söderlund

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C Nilsson

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G Lilja

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M Nordlund

Clinical and Experimental Immunology

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language of work or name

English

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publication date

December 2001

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published in

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volume

126

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issue

3

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page(s)

390-6

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cites work

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Higher risk of infantile atopic dermatitis from maternal atopy than from paternal atopy

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Innate recognition of bacteria in human milk is mediated by a milk-derived highly expressed pattern recognition receptor, soluble CD14

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Development of allergen-specific T-cell memory in atopic and normal children.

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Interleukin-12 is produced by dendritic cells and mediates T helper 1 development as well as interferon-gamma production by T helper 1 cells.

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Specific induction of interleukin-4-producing cells in response to in vitro allergen stimulation in atopic individuals

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Increased Frequencies of Allergen-Induced Interleukin-13-Producing Cells in Atopic Individuals During the Pollen Season

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Increased allergen-specific Th2 responses in vitro in atopic subjects receiving subclinical allergen challenge

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IgE in neonates is not suitable for general allergy risk screening

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Cord blood-IgE as risk factor and predictor for atopic diseases

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Fetal swallowing of IgE.

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Specific immunotherapy prevents increased levels of allergen-specific IL-4- and IL-13-producing cells during pollen season

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A Polymorphism* in the 5' flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E.

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Human peripheral blood contains two distinct lineages of dendritic cells.

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Selective expression of an interleukin-12 receptor component by human T helper 1 cells

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Mutations of the IL-12 receptor beta2 chain gene in atopic subjects

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Diminished expression of CD40 ligand by activated neonatal T cells

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Antibodies to the IL-12 receptor beta 2 chain mark human Th1 but not Th2 cells in vitro and in vivo

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Human dendritic cells require exogenous interleukin-12-inducing factors to direct the development of naive T-helper cells toward the Th1 phenotype.

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CD40 ligand is expressed and functional on activated neonatal T cells.

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IL-12 induces the production of IFN-gamma by neonatal human CD4 T cells.

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Maternal-fetal transfer of immunoglobulins

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IgE is expressed on, but not produced by, fetal cells in the human placenta irrespective of maternal atopy

2 November 2018

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Cytokines in breast milk from allergic and nonallergic mothers

30 November 2018

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12 December 2020

Mononuclear cell reactivity to food allergens in neonates, children and adults

1 reference

12 December 2020

Detection of IgA antibodies to cat, beta-lactoglobulin, and ovalbumin allergens in human milk

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12 December 2020

IL-4 Is a Mediator of IL-12p70 Induction by Human Th2 Cells: Reversal of Polarized Th2 Phenotype by Dendritic Cells

1 reference

12 December 2020

Impaired production of gamma-interferon by newborn cells in vitro is due to a functionally immature macrophage

1 reference

12 December 2020

Interferon-gamma production by cord-blood mononuclear cells is reduced in newborns with a family history of atopic disease and is independent from cord blood IgE-levels

1 reference

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Decreased expression of the ligand for CD40 in newborn lymphocytes

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12 December 2020

Reduced interferon-gamma secretion in neonates and subsequent atopy

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Maternal inheritance of atopy?

1 reference

12 December 2020

Fetal peripheral blood mononuclear cell proliferative responses to mitogenic and allergenic stimuli during gestation

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12 December 2020

Neonates at risk of atopy show impaired production of interferon-gamma after stimulation with bacterial products (LPS and SEE)

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12 December 2020

Influence of maternal infections with viral agents or Toxoplasma gondii during pregnancy on fetal IgE production

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12 December 2020

Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T cell responses toward the Th2 cytokine profile

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12 December 2020

Reciprocal control of T helper cell and dendritic cell differentiation

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12 December 2020