Impaired regulatory T cell function in germ-free mice (Q56901969)

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Carola Rask

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Susanne Hultkrantz

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Esbjörn Telemo

European Journal of Immunology

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language of work or name

English

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publication date

September 2006

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published in

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volume

36

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issue

9

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page(s)

2336-46

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cites work

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

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Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

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Oral tolerance: immune mechanisms and the generation of Th3-type TGF-beta-secreting regulatory cells

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High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells.

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Activated self-MHC-reactive T cells have the cytokine phenotype of Th3/T regulatory cell 1 T cells

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Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen

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Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity

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Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells

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The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells

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Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells

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A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function

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Induction of antigen-specific regulatory T cells in the liver-draining celiac lymph node following oral antigen administration.

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Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans.

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Demonstration of strong enterobacterial reactivity of CD4+CD25- T cells from conventional and germ-free mice which is counter-regulated by CD4+CD25+ T cells.

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Lessons from genetically engineered animal models. XII. IL-10-deficient (IL-10(-/-) mice and intestinal inflammation

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Regulation of TGF-beta response during T cell activation is modulated by IL-10

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Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected].

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The absence of gut flora, the doses of antigen ingested and aging affect the long-term peripheral tolerance induced by ovalbumin feeding in mice

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A full flora, but not monocolonization by Escherichia coli or lactobacilli, supports tolerogenic processing of a fed antigen.

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Control of intestinal inflammation by regulatory T cells

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Development and maintenance of the gut-associated lymphoid tissue (GALT): the roles of enteric bacteria and viruses

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Interactions of commensal gut microbes with subsets of B- and T-cells in the murine host

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Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency.

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Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells

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Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

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Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

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Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment

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Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

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Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

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Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells

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Toll-like receptor ligands directly promote activated CD4+ T cell survival

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7 January 2021

Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide

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Lipopolysaccharide induces CD25-positive, IL-10-producing lymphocytes without secretion of proinflammatory cytokines in the human colon: low MD-2 mRNA expression in colonic macrophages.

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Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells.

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Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens

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