Preferential dependence of autoantibody production in murine lupus on CD86 costimulatory molecule (Q56909292)

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19 October 2019

title

Preferential dependence of autoantibody production in murine lupus on CD86 costimulatory molecule (English)

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19 October 2019

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Nakajima A

1

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19 October 2019

Azuma M

2

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19 October 2019

Kodera S

3

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19 October 2019

Nuriya S

4

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19 October 2019

Terashi A

5

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19 October 2019

Abe M

6

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19 October 2019

Hirose S

7

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19 October 2019

Shirai T

8

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19 October 2019

Yagita H

9

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19 October 2019

Okumura K

10

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19 October 2019

language of work or name

English

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publication date

1 November 1995

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European Journal of Immunology

19 October 2019

published in

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19 October 2019

volume

25

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19 October 2019

issue

11

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19 October 2019

page(s)

3060-3069

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Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy

19 October 2019

cites work

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A cell culture model for T lymphocyte clonal anergy

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CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

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The role of the CD28 receptor during T cell responses to antigen

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B70 antigen is a second ligand for CTLA-4 and CD28.

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B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4.

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Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

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CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines

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B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells

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Mice transgenic for a soluble form of murine CTLA-4 show enhanced expansion of antigen-specific CD4+ T cells and defective antibody production in vivo

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7 January 2021

Induction of a cationic shift in IgG anti-DNA autoantibodies. Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis

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B-cell and T-cell function in systemic lupus erythematosus

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Treatment of murine lupus with CTLA4Ig

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B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

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7 January 2021

Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse

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7 January 2021

Effects of major histocompatibility complex on autoimmune disease of H-2-congenic New Zealand mice

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7 January 2021

CD5 B cells, a fetal B cell lineage

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Identifiers

DOI

10.1002/EJI.1830251112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7489744%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

1 reference