Influence of smoking and donor age on the spectrum of in vivo mutation at the HPRT-locus in T lymphocytes of healthy adults (Q57011538)

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3 November 2019

title

Influence of smoking and donor age on the spectrum of in vivo mutation at the HPRT-locus in T lymphocytes of healthy adults (English)

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3 November 2019

4

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3 November 2019

author name string

A Podlutsky

1

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3 November 2019

S M Hou

2

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3 November 2019

F Nyberg

3

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3 November 2019

B Lambert

5

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3 November 2019

language of work or name

English

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publication date

1 December 1999

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3 November 2019

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3 November 2019

volume

431

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3 November 2019

issue

2

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3 November 2019

page(s)

325-339

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The somatic mutation theory of ageing

3 November 2019

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Age and gender dependent levels of glutathione and glutathione S-transferases in human lymphocytes.

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Hprt mutant frequency and aromatic DNA adduct level in non-smoking and smoking lung cancer patients and population controls.

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Spectrum of somatic mutation at the hypoxanthine phosphoribosyltransferase (hprt) gene of healthy people.

7 January 2021

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Spectrum of point mutations in the coding region of the hypoxanthine-guanine phosphoribosyltransferase (hprt) gene in human T-lymphocytes in vivo.

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T-cell cloning to detect the mutant 6-thioguanine-resistant lymphocytes present in human peripheral blood

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Classification of mutations at the human hprt-locus in T-lymphocytes of bus maintenance workers by multiplex-PCR and reverse transcriptase-PCR analysis

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Statistical test for the comparison of samples from mutational spectra

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Analysis of mutations occurring at the human hprt locus.

7 January 2021

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Tandem double CC-->TT mutations are produced by reactive oxygen species

7 January 2021

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Enhanced hprt mutant frequency but no significant difference in mutation spectrum between a smoking and a non-smoking human population.

7 January 2021

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Are base substitution and frameshift mutagenesis pathways interrelated? An analysis based upon studies of the frequencies and specificities of mutations induced by the (+)-anti diol epoxide of benzo[a]pyrene

7 January 2021

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Sequence analysis of deletion mutations at the HPRT locus of human T-lymphocytes: association of a palindromic structure with a breakpoint cluster in exon 2

7 January 2021

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The effect of T-lymphocyte ‘clonality’ on the calculated hprt mutation frequency occurring in vivo in humans

7 January 2021

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Hprt activities and RNA phenotypes in 6-thioguanine resistant human T-lymphocytes.

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Transition mutations at CpG dinucleotides are the most frequent in vivo spontaneous single-based substitution mutation in the human HPRT gene

7 January 2021

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Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

7 January 2021

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Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers.

7 January 2021

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Strand specificity for mutations induced by (+)-anti BPDE in the hprt gene in human T-lymphocytes

7 January 2021

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7 January 2021

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7 January 2021

Identifiers

DOI

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3 November 2019

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