Cardiovascular safety of oral semaglutide in patients with type 2 diabetes: Rationale, design and patient baseline characteristics for the PIONEER 6 trial (Q57026289)

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scientific article published on 11 November 2018

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English	Cardiovascular safety of oral semaglutide in patients with type 2 diabetes: Rationale, design and patient baseline characteristics for the PIONEER 6 trial	scientific article published on 11 November 2018

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scholarly article

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26 April 2020

Cardiovascular safety of oral semaglutide in patients with type 2 diabetes: Rationale, design and patient baseline characteristics for the PIONEER 6 trial (English)

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26 April 2020

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type 2 diabetes

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1

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26 April 2020

Kathleen M Dungan

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Juan Francisco Merino-Torres

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Michael A Nauck

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author name string

Ofri Mosenzon

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26 April 2020

Rosario Arechavaleta

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26 April 2020

Pawel Bogdański

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26 April 2020

Abdurrahman Comlekci

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Agostino Consoli

6

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Chaicharn Deerochanawong

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Maria C Faingold

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26 April 2020

Michael E Farkouh

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26 April 2020

Denise R Franco

11

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Jeppe Gram

12

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Pankaj Joshi

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Rachid Malek

15

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26 April 2020

Sue D Pedersen

18

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26 April 2020

Robert J Silver

20

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26 April 2020

Cees J Tack

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26 April 2020

Nikhil Tandon

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26 April 2020

Ole K Jeppesen

23

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26 April 2020

Mette Strange

24

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26 April 2020

Mette Thomsen

25

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26 April 2020

Wayne H-H Sheu

19

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language of work or name

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publication date

11 November 2018

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26 April 2020

Diabetes, Obesity and Metabolism

1 reference

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26 April 2020

21

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26 April 2020

499-508

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3

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26 April 2020

A new equation to estimate glomerular filtration rate

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistence with injectable antidiabetic agents in members with type 2 diabetes in a commercial managed care organization

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A GLP-1 receptor agonist liraglutide inhibits endothelial cell dysfunction and vascular adhesion molecule expression in an ApoE-/- mouse model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral delivery of glucagon-like peptide-1 and analogs: alternatives for diabetes control?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

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Design of the liraglutide effect and action in diabetes: evaluation of cardiovascular outcome results (LEADER) trial.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment patterns among older patients with type 2 diabetes in the United States: a retrospective cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Management of hyperglycaemia in type 2 diabetes, 2015: a patient-centred approach. Update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-atherosclerotic effects of the glucagon-like peptide-1 (GLP-1) based therapies in patients with type 2 Diabetes Mellitus: A meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incretin therapies: highlighting common features and differences in the modes of action of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lixisenatide in Patients with Type 2 Diabetes and Acute Coronary Syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GLP-1 Agonists and Blood Pressure: A Review of the Evidence.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

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Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of once-weekly semaglutide versus once-daily insulin glargine as add-on to metformin (with or without sulfonylureas) in insulin-naive patients with type 2 diabetes (SUSTAIN 4): a randomised, open-label, parallel-group, multicentr

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes (SUSTAIN 2): a 56-week, double-blind, phase 3a, randomised trial.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Baseline characteristics of patients enrolled in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and baseline characteristics of participants in the Researching cardiovascular Events with a Weekly INcretin in Diabetes (REWIND) trial on the cardiovascular effects of dulaglutide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiovascular Actions and Clinical Outcomes With Glucagon-Like Peptide-1 Receptor Agonists and Dipeptidyl Peptidase-4 Inhibitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

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Effect of Oral Semaglutide Compared With Placebo and Subcutaneous Semaglutide on Glycemic Control in Patients With Type 2 Diabetes: A Randomized Clinical Trial.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiovascular outcomes with glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes: a meta-analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

8. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2018.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

9. Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes-2018.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

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Cardiovascular Outcomes Trials in Type 2 Diabetes: Where Do We Go From Here? Reflections From a Diabetes Care Editors' Expert Forum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of 6-month treatment with the glucagon like peptide-1 analogue liraglutide on arterial stiffness, left ventricular myocardial deformation and oxidative stress in subjects with newly diagnosed type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30284349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/DOM.13553

1 reference

Europe PubMed Central

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26 April 2020

1 reference

Europe PubMed Central

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26 April 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30284349%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

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