U2–U6 RNA folding reveals a group II intron-like domain and a four-helix junction (Q57080150)

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5 January 2020

title

U2-U6 RNA folding reveals a group II intron-like domain and a four-helix junction (English)

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2

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5 January 2020

Charles Mcmanus

3

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5 January 2020

author name string

Dipali G Sashital

1

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David A Brow

4

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5 January 2020

Samuel E Butcher

5

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publication date

14 November 2004

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Nature Structural & Molecular Biology

5 January 2020

published in

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volume

11

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issue

12

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page(s)

1237-1242

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https://scigraph.springernature.com/pub.10.1038/nsmb863

5 January 2020

exact match

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cites work

Allosteric cascade of spliceosome activation

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Self-splicing group II and nuclear pre-mRNA introns: how similar are they?

21 January 2018

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Evidence for two active sites in the spliceosome provided by stereochemistry of pre-mRNA splicing

21 January 2018

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The stereochemical course of group II intron self-splicing.

21 January 2018

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Spliceosomal snRNAs: Mg(2+)-dependent chemistry at the catalytic core?

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Characterization of the catalytic activity of U2 and U6 snRNAs

21 January 2018

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A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome

21 January 2018

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Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing.

21 January 2018

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Recognition of the TACTAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA.

21 January 2018

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Sculpting of the spliceosomal branch site recognition motif by a conserved pseudouridine

21 January 2018

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Mutations in U6 snRNA that alter splice site specificity: implications for the active site

21 January 2018

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A novel U2-U6 snRNA structure is necessary for mammalian mRNA splicing

21 January 2018

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Multiple functions for the invariant AGC triad of U6 snRNA.

21 January 2018

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The phylogenetically invariant ACAGAGA and AGC sequences of U6 small nuclear RNA are more tolerant of mutation in human cells than in Saccharomyces cerevisiae

21 January 2018

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Invariant U2 RNA sequences bordering the branchpoint recognition region are essential for interaction with yeast SF3a and SF3b subunits

21 January 2018

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A stem/loop in U6 RNA defines a conformational switch required for pre-mRNA splicing

21 January 2018

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Metal binding and base ionization in the U6 RNA intramolecular stem-loop structure

21 January 2018

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Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome.

21 January 2018

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Studies of point mutants define three essential paired nucleotides in the domain 5 substructure of a group II intron

21 January 2018

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Improving the accuracy of NMR structures of RNA by means of conformational database potentials of mean force as assessed by complete dipolar coupling cross-validation

21 January 2018

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Structure of the U6 RNA intramolecular stem–loop harboring an SP-phosphorothioate modification

21 January 2018

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Catalytically critical nucleotide in domain 5 of a group II intron

21 January 2018

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Structural insights into group II intron catalysis and branch-site selection

21 January 2018

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Solution structure of domain 5 of a group II intron ribozyme reveals a new RNA motif

21 January 2018

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The conserved central domain of yeast U6 snRNA: importance of U2-U6 helix Ia in spliceosome assembly

21 January 2018

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Point mutations in yeast U6 snRNA can specifically block the first or second step of pre-mRNA splicing in vitro

21 January 2018

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Conformational flexibility of four-way junctions in RNA.

21 January 2018

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Crystal structure of a hairpin ribozyme-inhibitor complex with implications for catalysis

21 January 2018

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mRNA-type introns in U6 small nuclear RNA genes: implications for the catalysis in pre-mRNA splicing.

21 January 2018

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Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns

21 January 2018

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Ribozyme catalysis from the major groove of group II intron domain 5.

21 January 2018

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Randomization-selection analysis of snRNAs in vivo: evidence for a tertiary interaction in the spliceosome

21 January 2018

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Filamentous bacteriophage for aligning RNA, DNA, and proteins for measurement of nuclear magnetic resonance dipolar coupling interactions

21 January 2018

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

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Structural Basis for a Lethal Mutation in U6 RNA † , ‡

21 January 2018

1 reference

The Xplor-NIH NMR molecular structure determination package

21 January 2018

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Involvement of U6 snRNA in 5' splice site selection

21 January 2018

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Functionally redundant interactions between U2 and U6 spliceosomal snRNAs

31 March 2020

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Metal ion binding sites in a group II intron core

31 March 2020

1 reference

Measurement of dipolar couplings for methylene and methyl sites in weakly oriented macromolecules and their use in structure determination

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB863

1 reference

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5 January 2020

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