VGX-1027 modulates genes involved in lipopolysaccharide-induced Toll-like receptor 4 activation and in a murine model of systemic lupus erythematosus (Q57081512)

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English	VGX-1027 modulates genes involved in lipopolysaccharide-induced Toll-like receptor 4 activation and in a murine model of systemic lupus erythematosus	article

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8 March 2020

VGX-1027 modulates genes involved in lipopolysaccharide-induced Toll-like receptor 4 activation and in a murine model of systemic lupus erythematosus (English)

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8 March 2020

toll-like receptor

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lipopolysaccharide

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inferred from title

systemic lupus erythematosus

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1

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8 March 2020

Karuppiah Muthumani

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8 March 2020

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8 March 2020

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8 March 2020

Pier Luigi Meroni

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8 March 2020

Niranjan Y Sardesai

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8 March 2020

David B. Weiner

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David B Weiner

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8 March 2020

Ferdinando Nicoletti

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Ferdinando Nicoletti

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ORCID Public Data File 2021

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Joseph J Kim

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8 March 2020

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1 August 2014

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8 March 2020

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8 March 2020

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8 March 2020

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8 March 2020

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8 March 2020

A potent immunomodulatory compound, (S,R)-3-Phenyl-4,5-dihydro-5-isoxazole acetic acid, prevents spontaneous and accelerated forms of autoimmune diabetes in NOD mice and inhibits the immunoinflammatory diabetes induced by multiple low doses of strep

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In vitro inhibition of enterobacteria-reactive CD4+CD25- T cells and suppression of immunoinflammatory colitis in mice by the novel immunomodulatory agent VGX-1027.

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Major pathogenic steps in human lupus can be effectively suppressed by nucleosomal histone peptide epitope-induced regulatory immunity

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Belimumab for the management of systemic lupus erythematosus

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Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus

1 reference

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The roles of interleukin-6 and interleukin-10 in B cell hyperactivity in systemic lupus erythematosus

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1 reference

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In vitro, ex vivo and in vivo immunopharmacological activities of the isoxazoline compound VGX-1027: Modulation of cytokine synthesis and prevention of both organ-specific and systemic autoimmune diseases in murine models

1 reference

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21 January 2018

Elevated levels of fractalkine expression and accumulation of CD16+ monocytes in glomeruli of active lupus nephritis

1 reference

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12 December 2020

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Killer Cell Immunoglobulin-like Receptor Workshop: Insights into Evolution, Genetics, Function, and Translation

1 reference

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12 December 2020

based on heuristic

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Functional characterization of peripheral blood dendritic cells and monocytes in systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/24527796

12 December 2020

based on heuristic

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Dichotomic effects of IFN-gamma on the development of systemic lupus erythematosus-like syndrome in MRL-lpr / lpr mice

1 reference

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12 December 2020

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Role of IL-10 in the abnormalities of early cell activation events of lymphocytes from patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/24527796

12 December 2020

based on heuristic

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