Collagenase-3 (MMP-13) and its activators in rheumatoid arthritis: localization in the pannus-hard tissue junction and inhibition by alendronate (Q57082646)

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scientific article published on 01 August 1999

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English	Collagenase-3 (MMP-13) and its activators in rheumatoid arthritis: localization in the pannus-hard tissue junction and inhibition by alendronate	scientific article published on 01 August 1999

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scholarly article

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1 November 2019

Collagenase-3 (MMP-13) and its activators in rheumatoid arthritis: localization in the pannus-hard tissue junction and inhibition by alendronate (English)

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1 November 2019

rheumatoid arthritis

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Carlos López Otín

11

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author name string

Konttinen YT

1

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Salo T

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Hanemaaijer R

3

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Valleala H

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Sorsa T

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Sutinen M

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Ceponis A

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Xu JW

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Santavirta S

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Teronen O

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publication date

1 August 1999

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4

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401-412

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1 November 2019

The synovium-cartilage junction of the normal human knee. Implications for joint destruction and repair

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The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

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Defective binding of macrophages to bone in rodent osteomalacia and vitamin D deficiency. In vitro evidence for a cellular defect and altered saccharides in the bone matrix.

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Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes)

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Localization of tumor necrosis factor receptors in the synovial tissue and cartilage-pannus junction in patients with rheumatoid arthritis. Implications for local actions of tumor necrosis factor alpha

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Matrix metalloproteinase-8 is expressed in rheumatoid synovial fibroblasts and endothelial cells. Regulation by tumor necrosis factor-alpha and doxycycline

1 reference

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7 January 2021

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Collagenases in human synovial fluid

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High levels of expression of collagenase-3 (MMP-13) in pathological conditions associated with a foreign-body reaction

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Biochemical characterization of human collagenase-3

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Cellular mechanisms for human procollagenase-3 (MMP-13) activation. Evidence that MT1-MMP (MMP-14) and gelatinase a (MMP-2) are able to generate active enzyme

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Collagenase reserves in polymorphonuclear neutrophil leukocytes from synovial fluid and peripheral blood of patients with rheumatoid arthritis

1 reference

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New collagenolytic enzymes/cascade identified at the pannus-hard tissue junction in rheumatoid arthritis: destruction from above

1 reference

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Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium

1 reference

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Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage

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The therapeutic effects of an engineered human anti-tumour necrosis factor alpha antibody (CDP571) in rheumatoid arthritis

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The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis

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Comparative immunolocalization studies of collagenase 1 and collagenase 3 production in the rheumatoid lesion, and by human chondrocytes and synoviocytes in vitro

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Constitutive expression of a 92-kD gelatinase (type V collagenase) by rheumatoid synovial fibroblasts and its induction in normal human fibroblasts by inflammatory cytokines

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2 Production of antisera with small doses of immunogen: multiple intradermal injections

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Tissue destruction by neutrophils

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Identifiers

10.1016/S0945-053X(99)00030-X

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Europe PubMed Central

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1 reference

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1 November 2019

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