Quantitative traits associated with the Type 2 diabetes susceptibility allele in Kir6.2 (Q57112357)

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5 November 2019

title

Quantitative traits associated with the Type 2 diabetes susceptibility allele in Kir6.2. (English)

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5 November 2019

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1

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5 November 2019

Anna Gloyn

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5 November 2019

Tim Frayling

3

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5 November 2019

George Davey Smith

5

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5 November 2019

author name string

A T Hattersley

4

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Y Ben-Shlomo

6

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publication date

18 June 2003

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5 November 2019

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5 November 2019

volume

46

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page(s)

1021-1023

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issue

7

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https://scigraph.springernature.com/pub.10.1007/s00125-003-1135-3

5 November 2019

exact match

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cites work

Morphological changes in pancreatic islets of KATP channel-deficient mice: the involvement of KATP channels in the survival of insulin cells and the maintenance of islet architecture

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12 December 2020

Of mice and men: K(ATP) channels and insulin secretion

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12 December 2020

E23K single nucleotide polymorphism in the islet ATP-sensitive potassium channel gene (Kir6.2) contributes as much to the risk of Type II diabetes in Caucasians as the PPARgamma Pro12Ala variant.

1 reference

12 December 2020

The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes

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12 December 2020

K(IR)6.2 polymorphism predisposes to type 2 diabetes by inducing overactivity of pancreatic beta-cell ATP-sensitive K(+) channels

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12 December 2020

Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

1 reference

12 December 2020

A putative functional polymorphism in the IGF-I gene: association studies with type 2 diabetes, adult height, glucose tolerance, and fetal growth in U.K. populations

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12 December 2020

Variations in insulin secretion in carriers of the E23K variant in the KIR6.2 subunit of the ATP-sensitive K(+) channel in the beta-cell

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12 December 2020

The prevalent Glu23Lys polymorphism in the potassium inward rectifier 6.2 (KIR6.2) gene is associated with impaired glucagon suppression in response to hyperglycemia

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12 December 2020

10.1007/S00125-003-1135-3

Identifiers

DOI

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5 November 2019

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