Prevention of spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice by intestinal-specific farnesoid X receptor reactivation (Q57147768)

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21 March 2020

title

Prevention of spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice by intestinal-specific farnesoid X receptor reactivation (English)

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3

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Antonio Moschetta

9

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21 March 2020

author name string

Chiara Degirolamo

1

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Salvatore Modica

2

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Giuseppe Di Tullio

4

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Annalisa Morgano

5

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Andria D'Orazio

6

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Kristina Kannisto

7

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Paolo Parini

8

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language of work or name

English

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publication date

30 October 2014

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21 March 2020

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volume

61

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issue

1

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page(s)

161-170

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Focus on hepatocellular carcinoma.

21 March 2020

cites work

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Hepatocellular carcinoma in cirrhosis: incidence and risk factors

21 January 2018

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Hepatocellular carcinoma in ten children under five years of age with bile salt export pump deficiency

21 January 2018

1 reference

Bile Acid Receptors and Liver Cancer

21 January 2018

1 reference

Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma

21 January 2018

1 reference

Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor

21 January 2018

1 reference

Bile-acid-induced cell injury and protection

21 January 2018

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Identification of a nuclear receptor for bile acids

21 January 2018

1 reference

Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

1 reference

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

Enterohepatic circulation of bile salts in farnesoid X receptor-deficient mice: efficient intestinal bile salt absorption in the absence of ileal bile acid-binding protein

21 January 2018

1 reference

Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice

21 January 2018

1 reference

Nuclear bile acid receptor FXR protects against intestinal tumorigenesis

21 January 2018

1 reference

Increased activation of the Wnt/β-catenin pathway in spontaneous hepatocellular carcinoma observed in farnesoid X receptor knockout mice

21 January 2018

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Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice

21 January 2018

1 reference

Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine

21 January 2018

1 reference

Hepatocyte-specific deletion of farnesoid X receptor delays but does not inhibit liver regeneration after partial hepatectomy in mice

21 January 2018

1 reference

Promotion of liver regeneration/repair by farnesoid X receptor in both liver and intestine in mice

21 January 2018

1 reference

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

21 January 2018

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Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlotho

21 January 2018

1 reference

Weaving betaKlotho into bile acid metabolism

21 January 2018

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Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1α regulation of FXR expression

21 January 2018

1 reference

Farnesoid X receptor deficiency induces nonalcoholic steatohepatitis in low-density lipoprotein receptor-knockout mice fed a high-fat diet

21 January 2018

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Deletion of IFNγ enhances hepatocarcinogenesis in FXR knockout mice

21 January 2018

1 reference

Small heterodimer partner overexpression partially protects against liver tumor development in farnesoid X receptor knockout mice.

21 January 2018

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Mechanisms of STAT3 activation in the liver of FXR knockout mice

21 January 2018

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Farnesoid X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response

21 January 2018

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Orphan receptor small heterodimer partner suppresses tumorigenesis by modulating cyclin D1 expression and cellular proliferation

21 January 2018

1 reference

Nuclear receptors in regenerating liver and hepatocellular carcinoma

21 January 2018

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Roles of microRNA-29a in the antifibrotic effect of farnesoid X receptor in hepatic stellate cells

21 January 2018

1 reference

Cirrhosis, bile acids and gut microbiota: unraveling a complex relationship.

21 January 2018

1 reference

Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor

21 January 2018

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Enhanced expression of farnesoid X receptor in human hepatocellular carcinoma

21 January 2018

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Downregulation of nuclear receptor FXR is associated with multiple malignant clinicopathological characteristics in human hepatocellular carcinoma

21 January 2018

1 reference

Synergistic growth inhibition of human hepatocellular carcinoma cells by acyclic retinoid and GW4064, a farnesoid X receptor ligand.

21 January 2018

1 reference

Downregulation of human farnesoid X receptor by miR-421 promotes proliferation and migration of hepatocellular carcinoma cells

21 January 2018

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Selective Activation of Nuclear Bile Acid Receptor FXR in the Intestine Protects Mice Against Cholestasis

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

FXR ligands protect against hepatocellular inflammation via SOCS3 induction

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Expression and prognostic roles of the G1-S modulators in hepatocellular carcinoma: p27 independently predicts the recurrence

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/HEP.27274

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21 March 2020

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