In vivo imaging of the spatiotemporal activity of the eIF2 -ATF4 signaling pathway: Insights into stress and related disorders (Q57174327)

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6 March 2020

title

In vivo imaging of the spatiotemporal activity of the eIF2α-ATF4 signaling pathway: Insights into stress and related disorders (English)

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10

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Philippe Ravassard

12

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Philippe Pierre

13

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author name string

Cédric Chaveroux

1

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Valérie Carraro

2

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Laurence Canaple

3

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Julien Averous

4

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Anne-Catherine Maurin

5

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Céline Jousse

6

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Yuki Muranishi

7

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Laurent Parry

8

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Florent Mesclon

9

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Jacques Mallet

11

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Pierre Fafournoux

14

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Alain Bruhat

15

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publication date

28 April 2015

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6 March 2020

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volume

8

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6 March 2020

issue

374

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page(s)

rs5

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The eIF2α kinases: their structures and functions

6 March 2020

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Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

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An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

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Coping with stress: eIF2 kinases and translational control

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ATF4-dependent transcription mediates signaling of amino acid limitation

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eIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress

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The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

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The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation.

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The GCN2 kinase biases feeding behavior to maintain amino acid homeostasis in omnivores

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Amino acid availability controls TRB3 transcription in liver through the GCN2/eIF2α/ATF4 pathway

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The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid.

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In vivo altered unfolded protein response and apoptosis in livers from lipopolysaccharide-challenged cirrhotic rats

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Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease

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Endoplasmic reticulum stress induced by hepatitis B virus X protein enhances cyclo-oxygenase 2 expression via activating transcription factor 4.

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GCN2 kinase is a key regulator of fibrogenesis and acute and chronic liver injury induced by carbon tetrachloride in mice.

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The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis

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The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.

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eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation.

21 January 2018

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ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress

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CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

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21 January 2018

Identifiers

DOI

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6 March 2020

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