Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients (Q57221897)

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16 February 2020

title

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype-positive rheumatoid arthritis patients (English)

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16 February 2020

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12

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16 February 2020

Anthony W. Purcell

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16 February 2020

Sanjoy K. Paul

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Kim-Anh Lê Cao

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16 February 2020

Ranjeny Thomas

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16 February 2020

author name string

Helen Benham

1

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16 February 2020

Soi Cheng Law

3

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16 February 2020

Shayna Street

5

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16 February 2020

Nishta Ramnoruth

6

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16 February 2020

Helen Pahau

7

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16 February 2020

Jennifer Ng

9

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16 February 2020

Claire Hyde

11

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16 February 2020

Hendrik J Nel

2

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16 February 2020

Ahmed M Mehdi

4

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16 February 2020

Bernett T Lee

8

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16 February 2020

Marion E G Brunck

10

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16 February 2020

Nadine L Dudek

13

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16 February 2020

Brendan J O'Sullivan

15

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16 February 2020

John E Connolly

16

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16 February 2020

language of work or name

English

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publication date

1 June 2015

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Science Translational Medicine

16 February 2020

published in

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16 February 2020

volume

7

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16 February 2020

page(s)

290ra87

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16 February 2020

issue

290

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16 February 2020

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Tight control in the treatment of rheumatoid arthritis: efficacy and feasibility

21 January 2018

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Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis.

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Antigen-specific induction of regulatory T cells in vivo and in vitro

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Epitope-specific immunotherapy of rheumatoid arthritis: clinical responsiveness occurs with immune deviation and relies on the expression of a cluster of molecules associated with T cell tolerance in a double-blind, placebo-controlled, pilot phase I

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Immunobiology of dendritic cells

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The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

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Genetics and epigenetics of rheumatoid arthritis

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Cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1*0401 MHC class II molecule

21 January 2018

1 reference

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T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles

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Response of Th17 cells to a citrullinated arthritogenic aggrecan peptide in patients with rheumatoid arthritis

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A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

21 January 2018

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Citrulline-specific Th1 cells are increased in rheumatoid arthritis and their frequency is influenced by disease duration and therapy

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1 reference

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Genome-wide association studies to advance our understanding of critical cell types and pathways in rheumatoid arthritis: recent findings and challenges

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T cells signaled by NF-kappa B- dendritic cells are sensitized not anergic to subsequent activation

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Trajectory of intensive treat-to-target disease modifying drug regimen in an observational study of an early rheumatoid arthritis cohort

21 January 2018

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Restoring the balance: immunotherapeutic combinations for autoimmune disease

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Rheumatoid arthritis: from palliation to remission in two decades

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Improving the safety of immunotherapy

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Homeostatic maintenance of T cells and natural killer cells

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Emerging cytokine targets in rheumatoid arthritis

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IL-7- and IL-15-mediated TCR sensitization enables T cell responses to self-antigens

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Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

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The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3

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Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling

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Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

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Correlation of CX3CL1 and CX3CR1 levels with response to infliximab therapy in patients with rheumatoid arthritis.

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Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy.

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Identification of self-antigen-specific T cells reflecting loss of tolerance in autoimmune disease underpins preventative immunotherapeutic strategies in rheumatoid arthritis

21 January 2018

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The interaction between HLA shared epitope alleles and smoking and its contribution to autoimmunity against several citrullinated antigens

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Anti-Sa antibodies and antibodies against cyclic citrullinated peptide are not equivalent as predictors of severe outcomes in patients with recent-onset polyarthritis

21 January 2018

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21 January 2018

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Differences in synovial tissue infiltrates between anti–cyclic citrullinated peptide–positive rheumatoid arthritis and anti–cyclic citrullinated peptide–negative rheumatoid arthritis

21 January 2018

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21 January 2018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26041704%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference