The Rapamycin and FKBP12 Target (RAFT) Displays Phosphatidylinositol 4-Kinase Activity (Q57371739)

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23 October 2019

title

The rapamycin and FKBP12 target (RAFT) displays phosphatidylinositol 4-kinase activity (English)

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23 October 2019

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Solomon Halbert Snyder

5

object named as

S H Snyder

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23 October 2019

1

D M Sabatini

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23 October 2019

author name string

B A Pierchala

2

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23 October 2019

R K Barrow

3

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23 October 2019

M J Schell

4

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23 October 2019

language of work or name

English

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publication date

1 September 1995

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Journal of Biological Chemistry

23 October 2019

published in

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23 October 2019

volume

270

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23 October 2019

issue

36

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23 October 2019

page(s)

20875-20878

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Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

23 October 2019

cites work

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Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

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Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

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Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

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Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

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RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

21 January 2018

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A mammalian protein targeted by G1-arresting rapamycin-receptor complex

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A Putative Sirolimus (Rapamycin) Effector Protein

21 January 2018

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RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex

21 January 2018

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Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

21 January 2018

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Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

21 January 2018

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Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity

21 January 2018

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Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

21 January 2018

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Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability

21 January 2018

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The Cerebral Microvessels in Culture, an Update

21 January 2018

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Immunological detection of glutamate receptor subtypes in human central nervous system

21 January 2018

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Changes in bioactive lipids, alkylacylglycerol and ceramide, occur in HIV-infected cells

21 January 2018

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21 January 2018

Phosphoinositide kinases

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Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes

21 January 2018

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PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

21 January 2018

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A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

21 January 2018

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Characterization of a phosphatidylinositol-specific phosphoinositide 3-kinase from mammalian cells

21 January 2018

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A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids

21 January 2018

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Multiple independent inputs are required for activation of the p70 S6 kinase

21 January 2018

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21 January 2018

Phospholipid signaling

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Phosphatidylinositol kinase is activated in membranes derived from cells treated with epidermal growth factor

21 January 2018

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Phosphoinositide kinase, diacylglycerol kinase, and phospholipase C activities associated to the cytoskeleton: effect of epidermal growth factor

21 January 2018

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Protein regulation by phosphatidylinositol lipids

21 January 2018

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A single ataxia telangiectasia gene with a product similar to PI-3 kinase

21 January 2018

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The sequence of phosphatidylinositol-4-phosphate 5-kinase defines a novel family of lipid kinases

21 January 2018

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Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.270.36.20875

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7673106%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

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