Interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: a randomised, double-blind, placebo-controlled trial (Q57374095)

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scientific article published in The Lancet

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English	Interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: a randomised, double-blind, placebo-controlled trial	scientific article published in The Lancet

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scholarly article

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4 January 2020

Interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: a randomised, double-blind, placebo-controlled trial (English)

1 reference

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4 January 2020

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multiple sclerosis

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based on heuristic

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placebo-controlled trial

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based on heuristic

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based on heuristic

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Massimo Filippi

1

1 reference

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4 January 2020

Stephen M. Smith

6

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4 January 2020

Frederik Barkhof

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Frederik Barkhof

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4 January 2020

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Giancarlo Comi

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4 January 2020

author name string

Marco Rovaris

2

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4 January 2020

Matilde Inglese

3

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4 January 2020

Nicola De Stefano

5

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4 January 2020

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publication date

1 October 2004

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4 January 2020

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4 January 2020

364

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4 January 2020

9444

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4 January 2020

1489-1496

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4 January 2020

Magnetic resonance techniques to monitor disease evolution and treatment trial outcomes in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantitative brain MRI lesion load predicts the course of clinically isolated syndromes suggestive of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The prognostic value of brain MRI in clinically isolated syndromes of the CNS. A 10-year follow-up.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

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A Longitudinal Study of Abnormalities on MRI and Disability from Multiple Sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

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Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Brain atrophy in relapsing multiple sclerosis: relationship to relapses, EDSS, and treatment with interferon beta-1a

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

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Optimizing the association between disability and biological markers in MS.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A longitudinal study of brain atrophy and cognitive disturbances in the early phase of relapsing-remitting multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Eight-year follow-up study of brain atrophy in patients with MS.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. CHAMPS Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of early interferon treatment on conversion to definite multiple sclerosis: a randomised study

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of ventricular enlargement in patients at the earliest clinical stage of MS

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Progressive ventricular enlargement in patients with clinically isolated syndromes is associated with the early development of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A neurologic rating scale (NRS) for use in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Magnetic resonance imaging in monitoring the treatment of multiple sclerosis: concerted action guidelines

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Intra-observer reproducibility in measuring new putative MR markers of demyelination and axonal loss in multiple sclerosis: a comparison with conventional T2-weighted images

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Normalized accurate measurement of longitudinal brain change.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Accurate, robust, and automated longitudinal and cross-sectional brain change analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The boundary shift integral: an accurate and robust measure of cerebral volume changes from registered repeat MRI.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Axonal transection in the lesions of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Interferon beta in the treatment of multiple sclerosis: mechanisms of action

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS. Multiple Sclerosis Collaborative Research Group

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Randomised double-blind placebo-controlled study of interferon β-1a in relapsing/remitting multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Inflammation in multiple sclerosis: the good, the bad, and the complex

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for widespread axonal damage at the earliest clinical stage of multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Longitudinal brain volume measurement in multiple sclerosis: rate of brain atrophy is independent of the disease subtype.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Age-related changes in conventional, magnetization transfer, and diffusion-tensor MR imaging findings: study with whole-brain tissue histogram analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Normal-appearing brain tissue MTR histograms in clinically isolated syndromes suggestive of MS.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Methylprednisolone effect on brain volume and enhancing lesions in MS before and during IFNbeta-1b

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The effect of gadolinium-enhancing lesions on whole brain atrophy in relapsing-remitting MS

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhancing magnetic resonance imaging lesions and cerebral atrophy in patients with relapsing multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Short-term brain volume change in relapsing-remitting multiple sclerosis: effect of glatiramer acetate and implications

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

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based on heuristic

inferred from DOI database lookup

Multiple sclerosis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2917271-1

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inferred from DOI database lookup

A comparison of the sensitivity of MRI after double- and triple-dose Gd-DTPA for detecting enhancing lesions in multiple sclerosis☆

1 reference

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based on heuristic

inferred from DOI database lookup

A histological, histochemical and biochemical study of the macroscopically normal white matter in multiple sclerosis

1 reference

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Induction of sodium channel clustering by oligodendrocytes

1 reference

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Synaptic efficacy enhanced by glial cells in vitro.

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inferred from DOI database lookup

Identifiers

10.1016/S0140-6736(04)17271-1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15500893%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15500893%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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