Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis (Q57378150)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9889120%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis (English)

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8 December 2019

3

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8 December 2019

author name string

L Englmeier

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9889120%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

J C Olivo

series ordinal

2

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8 December 2019

language of work or name

English

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publication date

1 January 1999

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8 December 2019

number of pages

12

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inferred from page(s)

published in

Current Biology

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8 December 2019

volume

9

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8 December 2019

page(s)

30-41

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8 December 2019

issue

1

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Identification of specific binding proteins for a nuclear location sequence

8 December 2019

cites work

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Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import

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Isolation of a protein that is essential for the first step of nuclear protein import

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A polypeptide domain that specifies migration of nucleoplasmin into the nucleus

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A short amino acid sequence able to specify nuclear location

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Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence

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Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins

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Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences

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Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha

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Sequence and characterization of cytoplasmic nuclear protein import factor p97

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Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope

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The nuclear pore-targeting complex binds to nuclear pores after association with a karyophile.

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Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins

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Distinct functions for the two importin subunits in nuclear protein import

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The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88

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7 January 2021

A novel class of RanGTP binding proteins

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Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor

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The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

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7 January 2021

CRM1 is an export receptor for leucine-rich nuclear export signals

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7 January 2021

The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus

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7 January 2021

Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor

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7 January 2021

Requirement of guanosine triphosphate-bound ran for signal-mediated nuclear protein export

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7 January 2021

Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins

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7 January 2021

Different binding domains for Ran-GTP and Ran-GDP/RanBP1 on nuclear import factor p97

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7 January 2021

Ran-binding protein 1 (RanBP1) forms a ternary complex with Ran and karyopherin beta and reduces Ran GTPase-activating protein (RanGAP) inhibition by karyopherin beta

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7 January 2021

Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins

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7 January 2021

Yrb4p, a yeast ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleus

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7 January 2021

Identification of a nuclear export receptor for tRNA

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7 January 2021

The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA

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7 January 2021

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

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7 January 2021

A yeast mutant which accumulates precursor tRNAs

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7 January 2021

RNA1 encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiae

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7 January 2021

RanGAP1 induces GTPase activity of nuclear Ras-related Ran

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7 January 2021

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

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7 January 2021

RanBP1 is crucial for the release of RanGTP from importin β-related nuclear transport factors

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7 January 2021

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

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7 January 2021

Nuclear PRP20 protein is required for mRNA export

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7 January 2021

Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily.

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7 January 2021

Diverse effects of the guanine nucleotide exchange factor RCC1 on RNA transport

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7 January 2021

Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import

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7 January 2021

The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly(A)+ RNA in the cytoplasm

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7 January 2021

Importin provides a link between nuclear protein import and U snRNA export.

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7 January 2021

Purification of a Ran-interacting protein that is required for protein import into the nucleus

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7 January 2021

The NTF2 gene encodes an essential, highly conserved protein that functions in nuclear transport in vivo

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7 January 2021

Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62

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7 January 2021

NTF2 mediates nuclear import of Ran.

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7 January 2021

Nuclear protein import

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7 January 2021

Nucleocytoplasmic transport: driving and directing transport.

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7 January 2021

Functions of the GTPase Ran in RNA export from the nucleus.

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7 January 2021

Nucleocytoplasmic transport: the soluble phase

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7 January 2021

Nucleocytoplasmic transport: the last 200 nanometers

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7 January 2021

Movement of a karyophilic protein through the nuclear pores of oocytes

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7 January 2021

Nuclear import can be separated into distinct steps in vitro: nuclear pore binding and translocation

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7 January 2021

Nuclear protein migration involves two steps: rapid binding at the nuclear envelope followed by slower translocation through nuclear pores

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2899%2980044-X

7 January 2021

Structural interaction between the nuclear pore complex and a specific translocating RNP particle

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7 January 2021

Sequential binding of import ligands to distinct nucleopore regions during their nuclear import.

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7 January 2021

The GLFG repetitive region of the nucleoporin Nup116p interacts with Kap95p, an essential yeast nuclear import factor

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7 January 2021

Major binding sites for the nuclear import receptor are the internal nucleoporin Nup153 and the adjacent nuclear filament protein Tpr

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7 January 2021

Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex

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7 January 2021

tRNA transport from the nucleus in a eukaryotic cell: carrier-mediated translocation process

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7 January 2021

Assembly in vitro of nuclei active in nuclear protein transport: ATP is required for nucleoplasmin accumulation.

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7 January 2021

A nuclear export signal in hnRNP A1: a signal-mediated, temperature-dependent nuclear protein export pathway

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7 January 2021

In vivo nuclear transport kinetics in Saccharomyces cerevisiae: a role for heat shock protein 70 during targeting and translocation

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7 January 2021

RAN/TC4 mutants identify a common requirement for snRNP and protein import into the nucleus

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7 January 2021

Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificities

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7 January 2021

Ran-unassisted nuclear migration of a 97-kD component of nuclear pore-targeting complex

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7 January 2021

Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis

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7 January 2021

A novel receptor-mediated nuclear protein import pathway

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7 January 2021

Energy- and temperature-dependent in vitro export of RNA from synthetic nuclei.

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7 January 2021

Nucleocytoplasmic shuttling factors including Ran and CRM1 mediate nuclear export of NFAT In vitro

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7 January 2021

Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors

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7 January 2021

A nuclear localization domain in the hnRNP A1 protein

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7 January 2021

The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

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7 January 2021

Identification of a signal for rapid export of proteins from the nucleus

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7 January 2021

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

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7 January 2021

Exportin 1 (Crm1p) is an essential nuclear export factor

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7 January 2021

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

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7 January 2021

Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA

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7 January 2021

The nuclear transport factor karyopherin beta binds stoichiometrically to Ran-GTP and inhibits the Ran GTPase activating protein

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7 January 2021

Nucleotide profiles of normal human blood cells determined by high-performance liquid chromatography

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7 January 2021

Identification of a tRNA-specific nuclear export receptor

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7 January 2021

The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic factors

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7 January 2021

RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import

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7 January 2021

Disassembly of RanGTP-karyopherin beta complex, an intermediate in nuclear protein import.

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7 January 2021

A pre-mRNA-binding protein accompanies the RNA from the gene through the nuclear pores and into polysomes.

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7 January 2021

A nuclear cap-binding complex binds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear export

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7 January 2021

Crystallization and preliminary X-ray diffraction analysis of nuclear transport factor 2.

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7 January 2021

Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1

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7 January 2021

10.1016/S0960-9822(99)80044-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9889120%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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