Calcineurin Increases Cardiac Transient Outward K+Currents via Transcriptional Up-regulation of Kv4.2 Channel Subunits (Q57396505)

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21 December 2019

title

Calcineurin increases cardiac transient outward K+ currents via transcriptional up-regulation of Kv4.2 channel subunits (English)

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21 December 2019

5

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21 December 2019

author name string

Nanling Gong

1

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21 December 2019

Ilona Bodi

2

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21 December 2019

Carsten Zobel

3

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21 December 2019

Arnold Schwartz

4

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21 December 2019

Peter H Backx

6

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21 December 2019

language of work or name

English

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publication date

23 October 2006

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Journal of Biological Chemistry

21 December 2019

number of pages

9

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based on heuristic

inferred from page(s)

published in

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21 December 2019

volume

281

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21 December 2019

issue

50

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21 December 2019

page(s)

38498-38506

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Role of heteromultimers in the generation of myocardial transient outward K+ currents.

21 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Regulation of KChIP2 potassium channel beta subunit gene expression underlies the gradient of transient outward current in canine and human ventricle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Transmural expression of transient outward potassium current subunits in normal and failing canine and human hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Amplification of spatial dispersion of repolarization underlies sudden cardiac death associated with catecholaminergic polymorphic VT, long QT, short QT and Brugada syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Regulation of cardiac excitation-contraction coupling by action potential repolarization: role of the transient outward potassium current (I(to)).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Prevention of hypertrophy by overexpression of Kv4.2 in cultured neonatal cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Interaction of angiotensin II with the angiotensin type 2 receptor inhibits the cardiac transient outward potassium current

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Molecular and functional signature of heart hypertrophy during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Basic mechanisms of atrial fibrillation--very new insights into very old ideas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Requirement of nuclear factor of activated T-cells in calcineurin-mediated cardiomyocyte hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Ca2+ controls functional expression of the cardiac K+ transient outward current via the calcineurin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

NFATc3-induced reductions in voltage-gated K+ currents after myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Cardiac function and electrical remodeling of the calcineurin-overexpressed transgenic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Effects of development and thyroid hormone on K+ currents and K+ channel gene expression in rat ventricle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Myocyte Enhancer Factors 2A and 2C Induce Dilated Cardiomyopathy in Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

GATA and FOG2 transcription factors differentially regulate the promoter for Kv4.2 K(+) channel gene in cardiac myocytes and PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Independent regulation of cardiac Kv4.3 potassium channel expression by angiotensin II and phenylephrine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Mitogen-activated protein kinases control cardiac KChIP2 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Increased regulatory activity of the calcineurin/NFAT pathway in human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Human atrial ion channel and transporter subunit gene-expression remodeling associated with valvular heart disease and atrial fibrillation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Overexpression of calcineurin in mouse causes sudden cardiac death associated with decreased density of K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Calcineurin and beyond: cardiac hypertrophic signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Inhibition of calcineurin and sarcolemmal Ca2+ influx protects cardiac morphology and ventricular function in K(v)4.2N transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

The molecular physiology of the cardiac transient outward potassium current (I(to)) in normal and diseased myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

Specific therapy based on the genotype and cellular mechanism in inherited cardiac arrhythmias. Long QT syndrome and Brugada syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607774200

21 January 2018

Identifiers

DOI

10.1074/JBC.M607774200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17060317%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference