Ligand-induced Structural Alterations in Human Iron Regulatory Protein-1 Revealed by Protein Footprinting (Q57397545)

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8 December 2019

title

Ligand-induced structural alterations in human iron regulatory protein-1 revealed by protein footprinting (English)

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8 December 2019

4

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8 December 2019

author name string

V Gegout

1

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8 December 2019

J Schlegl

2

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8 December 2019

B Schläger

3

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8 December 2019

J Reinbolt

5

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8 December 2019

B Ehresmann

6

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C Ehresmann

7

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P Romby

8

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8 December 2019

language of work or name

English

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publication date

1 May 1999

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Journal of Biological Chemistry

8 December 2019

published in

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8 December 2019

volume

274

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8 December 2019

page(s)

15052-15058

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8 December 2019

issue

21

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Enzymes as RNA-binding proteins: a role for (di)nucleotide-binding domains?

8 December 2019

cites work

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Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

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Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region

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Succinate dehydrogenase b mRNA of Drosophila melanogaster has a functional iron-responsive element in its 5'-untranslated region

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Translational regulation of mammalian and Drosophila citric acid cycle enzymes via iron-responsive elements

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Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation

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A specific mRNA binding factor regulates the iron-dependent stability of cytoplasmic transferrin receptor mRNA.

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Cloning and characterization of a mammalian proton-coupled metal-ion transporter

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Proteins binding to 5' untranslated region sites: a general mechanism for translational regulation of mRNAs in human and yeast cells

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IRP-1 Binding to Ferritin mRNA Prevents the Recruitment of the Small Ribosomal Subunit by the Cap-Binding Complex eIF4F

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A stem-loop in the 3' untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm.

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Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome

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Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: role of the iron-sulfur cluster

21 January 2018

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Expression of active iron regulatory factor from a full length human cDNA byin vitrotranscription/translation

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A regulated RNA binding protein also possesses aconitase activity

21 January 2018

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Purification and characterization of cytosolic aconitase from beef liver and its relationship to the iron-responsive element binding protein

21 January 2018

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Iron regulatory factor expressed from recombinant baculovirus: conversion between the RNA-binding apoprotein and Fe-S cluster containing aconitase

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The iron-sulfur cluster of iron regulatory protein 1 modulates the accessibility of RNA binding and phosphorylation sites

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Homology between IRE-BP, a regulatory RNA-binding protein, aconitase, and isopropylmalate isomerase

21 January 2018

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Crystal structures of aconitase with isocitrate and nitroisocitrate bound

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The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation

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Localization of an RNA binding element of the iron responsive element binding protein within a proteolytic fragment containing iron coordination ligands

21 January 2018

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A novel method to identify nucleic acid binding sites in proteins by scanning mutagenesis: application to iron regulatory protein

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The iron-responsive element-binding protein: localization of the RNA-binding site to the aconitase active-site cleft

21 January 2018

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Iron-sulphur clusters as genetic regulatory switches: the bifunctional iron regulatory protein-1.

21 January 2018

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Recombinant iron-regulatory factor functions as an iron-responsive-element-binding protein, a translational repressor and an aconitase. A functional assay for translational repression and direct demonstration of the iron switch

21 January 2018

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Modulation of the RNA-binding activity of a regulatory protein by iron in vitro: switching between enzymatic and genetic function?

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Mapping protein domains involved in macromolecular interactions: a novel protein footprinting approach.

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Intermolecular binding sites of human immunodeficiency virus type 1 Rev protein determined by protein footprinting.

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Structural requirements of iron-responsive elements for binding of the protein involved in both transferrin receptor and ferritin mRNA post-transcriptional regulation

21 January 2018

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Ferritin mRNA: interactions of iron regulatory element with translational regulator protein P-90 and the effect on base-paired flanking regions

21 January 2018

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The interaction between the iron-responsive element binding protein and its cognate RNA is highly dependent upon both RNA sequence and structure

21 January 2018

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Cloning of the cDNA encoding an RNA regulatory protein--the human iron-responsive element-binding protein

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.21.15052

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10329709%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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