Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes (Q57472089)

Annik Prat

19

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Thorbald van Hall

Thorbald van Hall

13

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Sjaak Neefjes

Jacques Neefjes

21

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Peter van Veelen

Peter A van Veelen

26

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Cornelis J. M. Melief

28

Cornelis J M Melief

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Kees L M C Franken

10

Kees L M C Franken

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Ferry Ossendorp

27

Ferry Ossendorp

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Selina Khan

2

Selina Khan

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Jan W Drijfhout

25

Jan W Drijfhout

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author name string

Jan H Kessler

1

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Ulrike Seifert

3

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K Martin Chow

5

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Annette Paschen

6

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Sandra A Bres-Vloemans

7

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Arnoud de Ru

8

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Nadine van Montfoort

9

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Willemien E Benckhuijsen

11

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Jill M Brooks

12

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Kallol Ray

14

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Arend Mulder

15

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Ilias I N Doxiadis

16

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Paul F van Swieten

17

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Hermen S Overkleeft

18

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Birgitta Tomkinson

20

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Peter M Kloetzel

22

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David W Rodgers

23

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Louis B Hersh

Post-proteasomal antigen processing for major histocompatibility complex class I presentation

24

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language of work or name

English

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publication date

12 December 2010

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published in

Nature Immunology

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volume

12

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issue

1

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page(s)

45-53

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cites work

1 reference

All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen-processing pathway

21 January 2018

1 reference

Plumbing the sources of endogenous MHC class I peptide ligands

21 January 2018

1 reference

A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation.

21 January 2018

1 reference

The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation

21 January 2018

1 reference

Pathway for degradation of peptides generated by proteasomes: a key role for thimet oligopeptidase and other metallopeptidases

21 January 2018

1 reference

Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.

21 January 2018

1 reference

Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide

21 January 2018

1 reference

The selective proteasome inhibitors lactacystin and epoxomicin can be used to either up- or down-regulate antigen presentation at nontoxic doses

21 January 2018

1 reference

Differences in the expression of human class I MHC alleles and their associated peptides in the presence of proteasome inhibitors

21 January 2018

1 reference

Proteasome-independent HLA-B27 ligands arise mainly from small basic proteins

21 January 2018

1 reference

An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope.

21 January 2018

1 reference

Production of an antigenic peptide by insulin-degrading enzyme

21 January 2018

1 reference

Role of tripeptidyl peptidase II in MHC class I antigen processing - the end of controversies?

21 January 2018

1 reference

Modeling the MHC class I pathway by combining predictions of proteasomal cleavage, TAP transport and MHC class I binding

21 January 2018

1 reference

Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis.

21 January 2018

1 reference

A giant protease with potential to substitute for some functions of the proteasome

21 January 2018

1 reference

Human NRD convertase: a highly conserved metalloendopeptidase expressed at specific sites during development and in adult tissues

21 January 2018

1 reference

Studies on the subsite specificity of rat nardilysin (N-arginine dibasic convertase).

21 January 2018

1 reference

Nardilysin cleaves peptides at monobasic sites

21 January 2018

1 reference

Thimet oligopeptidase specificity: evidence of preferential cleavage near the C-terminus and product inhibition from kinetic analysis of peptide hydrolysis

21 January 2018

1 reference

Temperature and salts effects on the peptidase activities of the recombinant metallooligopeptidases neurolysin and thimet oligopeptidase

21 January 2018

1 reference

Substrate specificity characterization of recombinant metallo oligo-peptidases thimet oligopeptidase and neurolysin

21 January 2018

1 reference

HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1.

21 January 2018

1 reference

Different HLA-B27 subtypes present the same immunodominant Epstein-Barr virus peptide

21 January 2018

1 reference

Flexibility in substrate recognition by thimet oligopeptidase as revealed by denaturation studies

21 January 2018

1 reference

Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes

21 January 2018

1 reference

Portable flanking sequences modulate CTL epitope processing

21 January 2018

1 reference

Thimet oligopeptidase and the stability of MHC class I epitopes in macrophage cytosol.

21 January 2018

1 reference

Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase

21 January 2018

1 reference

Regulation of cell-surface major histocompatibility complex class I expression by the endopeptidase EC3.4.24.15 (thimet oligopeptidase).

21 January 2018

1 reference

Analysis of intracellular substrates and products of thimet oligopeptidase in human embryonic kidney 293 cells.

21 January 2018

1 reference

Cutting edge: HLA-B27 acquires many N-terminal dibasic peptides: coupling cytosolic peptide stability to antigen presentation.

21 January 2018

1 reference

Competition-based cellular peptide binding assays for 13 prevalent HLA class I alleles using fluorescein-labeled synthetic peptides

21 January 2018

1 reference

Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic beta-subunits

21 January 2018

1 reference

Immunological cross-reactivity between human tripeptidyl peptidase II and fibronectin

21 January 2018

1 reference

Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling

21 January 2018

1 reference

Human transporters associated with antigen processing possess a promiscuous peptide-binding site

21 January 2018

1 reference

A cell-permeable inhibitor and activity-based probe for the caspase-like activity of the proteasome

21 January 2018

1 reference

Purification, substrate specificity, and classification of tripeptidyl peptidase II.

21 January 2018

1 reference

12 December 2020

Thimet oligopeptidase (EC 3.4.24.15), a novel protein on the route of MHC class I antigen presentation

1 reference

12 December 2020

Proteasomes can either generate or destroy MHC class I epitopes: evidence for nonproteasomal epitope generation in the cytosol

1 reference

12 December 2020

Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences

1 reference

12 December 2020

Generation of the vesicular stomatitis virus nucleoprotein cytotoxic T lymphocyte epitope requires proteasome-dependent and -independent proteolytic activities

1 reference

12 December 2020

Overlapping peptides of melanocyte differentiation antigen Melan-A/MART-1 recognized by autologous cytolytic T lymphocytes in association with HLA-B45.1 and HLA-A2.1.

1 reference

12 December 2020

Distinct proteolytic processes generate the C and N termini of MHC class I-binding peptides.

1 reference

12 December 2020

Human monoclonal HLA antibodies reveal interspecies crossreactive swine MHC class I epitopes relevant for xenotransplantation

1 reference

12 December 2020

Allelic differences in the relationship between proteasome activity and MHC class I peptide loading.

1 reference

12 December 2020

Regulation of N-arginine dibasic convertase activity by amines: putative role of a novel acidic domain as an amine binding site

1 reference

12 December 2020

Cytolytic T lymphocyte recognition of the immunodominant HLA-A*0201-restricted Melan-A/MART-1 antigenic peptide in melanoma.

1 reference

12 December 2020